Jin'an Zhao, Yamei Gao, Huanli Yang
Weinan Central Hospital 714000, China.
Open Med (Wars). 2015 Dec 17;10(1):416-420. doi: 10.1515/med-2015-0072. eCollection 2015.
To discuss the feasibility and safety of prophylactic tentorium cerebelli hiatus incision in surgery of glioma located in lateral fissure area. There were 80 patients with glioma located in lateral fissure area who received treatment from May 2012 to May 2015, divided into two groups, the research group (n=40) and control group (n=40), and then statistical analysis was carried out. Difference in total resection rate and subtotal resection rate of glioma between patients of the research group and those of the control group was not significant (P>0.05); intracranial pressure of patients in the research group was significantly lower than that of control group (P<0.05), their hospital stay was significantly shorter than that of the control group (P<0.05), times of using mannitol were significantly fewer than control group (P<0.05), but the differences of acute renal function damage and second surgery occurrence rate between patients of the two groups were not significant (P>0.05). Prophylactic tentorium cerebelli hiatus incision in surgery of glioma located in lateral fissure area can effectively reduce patients' intracranial pressure, shorten patients' hospital stay and reduce patients' times of using mannitol without increasing the rate of patients' acute renal function damage and second surgery.
探讨预防性小脑幕裂孔切开术在外侧裂区胶质瘤手术中的可行性及安全性。选取2012年5月至2015年5月期间收治的80例外侧裂区胶质瘤患者,分为研究组(n = 40)和对照组(n = 40),然后进行统计学分析。研究组患者与对照组患者胶质瘤的全切除率和次全切除率差异无统计学意义(P > 0.05);研究组患者的颅内压显著低于对照组(P < 0.05),住院时间显著短于对照组(P < 0.05),甘露醇使用次数显著少于对照组(P < 0.05),但两组患者急性肾功能损害及二次手术发生率差异无统计学意义(P > 0.05)。预防性小脑幕裂孔切开术应用于外侧裂区胶质瘤手术可有效降低患者颅内压,缩短患者住院时间,减少患者甘露醇使用次数,且不增加患者急性肾功能损害及二次手术发生率。