Zhang Yan, Lv Qing, Qi Meiling, Cai Zhiqiang
Key Laboratory of Cluster Science, Ministry of Education of China, Beijing Key Laboratory of Photoelectronic/Electrophotonic Conversion Materials and School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing 100081, China.
Key Laboratory of Cluster Science, Ministry of Education of China, Beijing Key Laboratory of Photoelectronic/Electrophotonic Conversion Materials and School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing 100081, China.
J Chromatogr A. 2017 May 5;1496:115-121. doi: 10.1016/j.chroma.2017.03.054. Epub 2017 Mar 22.
This work presents the investigation of permethyl pillar[5]arene (MP5) as stationary phase for capillary gas chromatographic (GC) separations. The MP5 capillary column fabricated by the sol-gel coating method exhibited weak polarity and high column efficiency over 4200 plates/m for n-dodecane, n-octanol and naphthalene. Particularly, the MP5 stationary phase displays unique retention for dibromoalkanes, which was found to be closely related with the linker length, and shows high resolving capability for a wide range of positional and structural isomers, including alkylbenzenes, chlorobenzenes and chloronitrobenzenes, naphthalene derivatives, phenols and anilines. Moreover, the MP5 column showed good thermal stability and repeatability and reproducibility with the relative standard deviation in the range of 0.02-0.04% for intra-day, 0.32-0.46% for inter-day and 1.5-3.4% for between-column, respectively. This work demonstrates an promising future of pillar[n]arenes as a new type of stationary phase in chromatographic separations.
本研究对全甲基化柱[5]芳烃（MP5）作为毛细管气相色谱（GC）分离的固定相进行了考察。通过溶胶-凝胶涂覆法制备的MP5毛细管柱显示出弱极性，对正十二烷、正辛醇和萘的柱效超过4200理论塔板数/米。特别地，MP5固定相对二溴烷烃表现出独特的保留行为，这被发现与连接链长度密切相关，并且对包括烷基苯、氯苯和氯硝基苯、萘衍生物、酚类和苯胺类在内的各种位置异构体和结构异构体具有高分离能力。此外，MP5柱显示出良好的热稳定性以及日内、日间和柱间的重复性和重现性，相对标准偏差分别在0.02 - 0.04%、0.32 - 0.46%和1.5 - 3.4%范围内。本研究证明了柱[n]芳烃作为色谱分离中新型固定相具有广阔的前景。
