Li Wen, Ba Mengyi, Song Yanli, Zhang Yuanyuan, Xu Xiang, Liu Haixin, Li Leyao, Liu Xinyi, Cai Zhiqiang, Sun Tao
Liaoning Province Professional and Technical Innovation Center for Fine Chemical Engineering of Aromatics Downstream, School of Petrochemical Engineering, Shenyang University of Technology, Liaoyang, 111003, P. R. China.
College of Chemistry and Chemical Engineering, Henan Key Laboratory of Function-Oriented Porous Materials, Luoyang Normal University, Luoyang, 471934, P. R. China.
Chem Biodivers. 2024 Mar;21(3):e202301795. doi: 10.1002/cbdv.202301795. Epub 2024 Feb 9.
This work reports the first example of employing ester-functionalized pillar[5]arene (P5A-C10-OAc) stationary phase for gas chromatography (GC) separations. The as-fabricated P5A-C10-OAc column achieved improved column efficiency of 4270 plates/m and separation performance in contrast to the P5-C10-Br column. The P5A-C10-OAc column showed good separation performance for a wide range of analytes such as alkanes, bromoalkanes, ketones, fatty acid methyl esters, aldehydes, alcohols, halobenzenes, anilines, phenols, naphthalenes, and showed sharp and symmetrical peak shapes for analytes that are liable to peak-tailing in GC analysis. As testified by the challenging isomer mixtures (bromonitrobenzene, chloronitrobenzene, bromobenzaldehyde, chlorobenzaldehyde, nitrobenzaldehyde), the P5A-C10-OAc column exhibited comprehensively higher separation capability than the P5A-C10-Br, P5A-C10 and commercial HP-35 columns. This work demonstrates the great potential of pillararene-based stationary phases as a new type of stationary phases for GC separations.
这项工作报道了首例将酯功能化柱[5]芳烃（P5A-C10-OAc）固定相用于气相色谱（GC）分离的实例。与P5-C10-Br柱相比，所制备的P5A-C10-OAc柱实现了4270塔板数/米的更高柱效和分离性能。P5A-C10-OAc柱对多种分析物，如烷烃、溴代烷烃、酮类、脂肪酸甲酯、醛类、醇类、卤代苯、苯胺、酚类、萘类等，均表现出良好的分离性能，并且对于在GC分析中易于出现峰拖尾的分析物呈现出尖锐且对称的峰形。通过具有挑战性的异构体混合物（溴硝基苯、氯硝基苯、溴苯甲醛、氯苯甲醛、硝基苯甲醛）验证，P5A-C10-OAc柱展现出比P5A-C10-Br、P5A-C10和商用HP-35柱综合更高的分离能力。这项工作证明了基于柱芳烃的固定相作为一种新型GC分离固定相具有巨大潜力。
