评估2-氰基丙烯酸辛酯在单侧唇裂修复中的应用。

Evaluating the use of octyl-2-cyanoacrylate in unilateral cleft lip repair.

作者信息

Malhotra Vijaylaxmy, Dayashankara Rao J K, Arya Varun, Sharma Shalender, Singh Sushil, Luthra Payal

机构信息

Department of Oral and Maxillofacial Surgery, S.H.K.M. Government Medical College, Nalhar, Haryana, India.

Department of Oral and Maxillofacial Surgery, SGT Dental College, Gurgaon, Haryana, India.

出版信息

Natl J Maxillofac Surg. 2016 Jul-Dec;7(2):153-158. doi: 10.4103/0975-5950.201364.

Abstract

BACKGROUND

Facial cosmetic results are one of the most concerning issues for the parents who get their children operated for cleft lip. Moreover, the postoperative care of the surgical site, the discomfort associated with the suture removal, and additional visit for suture removal are other reasons which encourages one to use any new technologies that may replace the need for suture placement. In this study, we used octyl-2-cyanoacrylate, a tissue adhesive which offers a viable alternative to traditional techniques without compromising optimal wound closure.

OBJECTIVE

To perform a comprehensive comparison of the outcomes from the use of Dermabond in patients undergoing primary repair of congenital cleft lip ± palate anomalies.

MATERIALS AND METHODS

Twenty patients, in the age group of 3-18 months were treated surgically for unilateral cleft lip deformity using Millard rotation-advancement flap. Pre- and post-operative photographs of the patients were taken at 1 week, 2 week, 1 month, 6 months, and 1 year postoperatively and were evaluated using Vancouver scar scale which was given by Sullivan in 1990. Paired -test was used for statistical analysis.

RESULTS

Increased vascularity (hyperemia) was seen in the 1 and 2 week in 35% and 30% patients, respectively which gradually reduced to normal in subsequent follow-ups. The scar was flat in 85% of patients in 1 week, and the number decreased to 10% at the end of 1 year. No wound dehiscence was found in any patients. Statistical analysis showed that among all the follow-ups, only the difference between the first and second follow-ups. Comparison of the results of 1 week with all other follow-ups yielded no significant results.

CONCLUSION

Octyl-2-cyanoacrylate can be used for cleft lip closure effectively. The procedure is relatively painless and quick. Added to this are benefits of protection from wound infection since the material is bacteriostatic.

摘要

背景

面部美容效果是为唇裂患儿进行手术的家长最关心的问题之一。此外,手术部位的术后护理、拆线时的不适以及额外的拆线就诊也是促使人们使用任何可能替代缝线放置需求的新技术的其他原因。在本研究中,我们使用了2-氰基丙烯酸辛酯,这是一种组织粘合剂,它为传统技术提供了可行的替代方案,同时不影响最佳伤口闭合效果。

目的

对使用皮肤粘合剂治疗先天性唇裂±腭裂畸形一期修复患者的结果进行全面比较。

材料与方法

20例年龄在3至18个月的患者接受了单侧唇裂畸形的手术治疗,采用米勒旋转推进皮瓣。在术后1周、2周、1个月、6个月和1年拍摄患者的术前和术后照片,并使用1990年沙利文给出的温哥华瘢痕量表进行评估。采用配对t检验进行统计分析。

结果

分别有35%和30%的患者在第1周和第2周出现血管增生(充血),在随后的随访中逐渐恢复正常。85%的患者在1周时瘢痕变平到1年末降至10%在任何患者中均未发现伤口裂开。统计分析表明,在所有随访中只有第一次和第二次随访之间存在差异将1周时的结果与所有其他随访结果进行比较未得出显著结果。

结论

2-氰基丙烯酸辛酯可有效用于唇裂闭合。该过程相对无痛且快速。此外,由于该材料具有抑菌作用,还有预防伤口感染的益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50e1/5357920/8cf167a3c13b/NJMS-7-153-g001.jpg

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