Saxena Anurag, Dubey Manish, Saha Gaurav K, Tiwari Devesh, Tyagi Shaily, Singh Roseneel A
Agamya Dental Clinic and Implant Centre, Lucknow, Uttar Pradesh, India.
Department of Dentistry, T.S Misra Medical College and Hospital, Lucknow, Uttar Pradesh, India.
J Pharm Bioallied Sci. 2023 Jul;15(Suppl 2):S1145-S1148. doi: 10.4103/jpbs.jpbs_187_23. Epub 2023 Jul 11.
The study aimed to evaluate the efficacy of octyl-2-cyanoacrylate as well as sutures as a wound closure material. Whether octyl-2-cyanoacrylate can be used as an alternative to suture in the closure of facial wounds. Out of total of 19 wounds, 11 wounds were closed with sutures and tissue adhesive both, out of rest 8 wounds, 4 wounds were closed using sutures alone and in 4 wounds, closure was done with tissue adhesive alone. Therefore, a total of 15 facial wounds were divided into two groups: Group-I Cases in whom 3-0 Black silk suture was used for closure of the wound and Group-II Cases in whom Dermabond (Octyl-2-Cyanoacrylate) was used for closure of the wound. Results showed that Octyl-2-cyanoacrylate offered the benefit of decreased procedure time with less pain, no need for its removal, and better cosmetic outcome compared to sutures.
该研究旨在评估2-氰基丙烯酸辛酯以及缝线作为伤口闭合材料的疗效。2-氰基丙烯酸辛酯是否可作为面部伤口闭合中缝线的替代品。在总共19处伤口中，11处伤口同时使用缝线和组织粘合剂进行闭合，在其余8处伤口中，4处伤口仅使用缝线闭合，4处伤口仅使用组织粘合剂闭合。因此，总共15处面部伤口被分为两组：第一组病例使用3-0黑色丝线缝合伤口，第二组病例使用皮肤粘合剂（2-氰基丙烯酸辛酯）闭合伤口。结果表明，与缝线相比，2-氰基丙烯酸辛酯具有减少手术时间、疼痛减轻、无需拆线以及美容效果更好的优点。
