- 肿瘤坏死因子：一种致命诱惑。 - Suppr

- tumor necrosis factor: a fatal attraction.

作者信息

Ankri Serge

机构信息

Department of Molecular Microbiology, Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.

出版信息

Microb Cell. 2015 Jul 6;2(7):216-218. doi: 10.15698/mic2015.07.216.

DOI:10.15698/mic2015.07.216

PMID:28357296

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5349168/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b8c/5349168/b27fed165515/mic-02-216-g01.jpg

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- tumor necrosis factor: a fatal attraction.- 肿瘤坏死因子：一种致命诱惑。

Microb Cell. 2015 Jul 6;2(7):216-218. doi: 10.15698/mic2015.07.216.

In , a BspA family protein is required for chemotaxis toward tumour necrosis factor.在……中，一种BspA家族蛋白是对肿瘤坏死因子进行趋化作用所必需的。

Microb Cell. 2015 Jul 6;2(7):235-246. doi: 10.15698/mic2015.07.214.

Characteristics of inflammatory reactions during development of liver abscess in hamsters inoculated with Entamoeba nuttalli.感染纳氏内阿米巴后仓鼠肝脓肿形成过程中炎症反应的特点。

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Entamoeba histolytica Interaction with Enteropathogenic Escherichia coli Increases Parasite Virulence and Inflammation in Amebiasis.溶组织内阿米巴与肠致病性大肠杆菌的相互作用增加了阿米巴病的寄生虫毒力和炎症。

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Transcriptomic analysis reveals novel downstream regulatory motifs and highly transcribed virulence factor genes of Entamoeba histolytica.转录组分析揭示了溶组织内阿米巴的新型下游调控基序和高度转录的毒力因子基因。

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Entamoeba histolytica stimulates the unstable transcription of c-fos and tumour necrosis factor-alpha mRNA by protein kinase C signal transduction in macrophages.溶组织内阿米巴通过蛋白激酶C信号转导刺激巨噬细胞中c-fos和肿瘤坏死因子-α mRNA的不稳定转录。

Immunology. 1995 Sep;86(1):49-57.

In vitro effect of human recombinant tumor necrosis factor on Entamoeba histolytica trophozoites.

Immunobiology. 1990 Jun;180(4-5):339-50. doi: 10.1016/S0171-2985(11)80297-4.

Morphometric study of the hepatic lesions experimentally induced in hamsters by Entamoeba dispar and E. histolytica.对由溶组织内阿米巴和迪斯帕内阿米巴在仓鼠中实验诱导产生的肝脏病变的形态计量学研究。

Parasite. 2007 Dec;14(4):329-34. doi: 10.1051/parasite/2007144329.

Initiation of inflammation and cell death during liver abscess formation by Entamoeba histolytica depends on activity of the galactose/N-acetyl-D-galactosamine lectin.溶组织内阿米巴导致肝脓肿形成过程中炎症和细胞死亡的起始取决于半乳糖/N-乙酰-D-半乳糖胺凝集素的活性。

Int J Parasitol. 2007 Mar;37(3-4):425-33. doi: 10.1016/j.ijpara.2006.10.008. Epub 2006 Nov 21.

Differential expression of pathogenic genes of Entamoeba histolytica vs E. dispar in a model of infection using human liver tissue explants.在使用人肝组织外植体的感染模型中，溶组织内阿米巴与迪斯帕内阿米巴致病基因的差异表达

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mBio. 2017 Oct 3;8(5):e01323-17. doi: 10.1128/mBio.01323-17.

本文引用的文献

The parasite Entamoeba histolytica exploits the activities of human matrix metalloproteinases to invade colonic tissue.寄生虫溶组织内阿米巴利用人类基质金属蛋白酶的活性来侵袭结肠组织。

Nat Commun. 2014 Oct 7;5:5142. doi: 10.1038/ncomms6142.

Regulation of virulence of Entamoeba histolytica.溶组织内阿米巴毒力的调控

Annu Rev Microbiol. 2014;68:493-520. doi: 10.1146/annurev-micro-091313-103550. Epub 2014 Jun 16.

The macrophage migration inhibitory factor homolog of Entamoeba histolytica binds to and immunomodulates host macrophages.溶组织内阿米巴巨噬细胞移动抑制因子同源物与宿主巨噬细胞结合并调节其免疫功能。

Infect Immun. 2014 Sep;82(9):3523-30. doi: 10.1128/IAI.01812-14. Epub 2014 May 12.

Identification of the virulence landscape essential for Entamoeba histolytica invasion of the human colon.鉴定与溶组织内阿米巴感染人类结肠相关的毒力特征。

PLoS Pathog. 2013;9(12):e1003824. doi: 10.1371/journal.ppat.1003824. Epub 2013 Dec 19.

Entamoeba histolytica exacerbates epithelial tight junction permeability and proinflammatory responses in Muc2(-/-) mice.溶组织内阿米巴加剧 Muc2(-/-) 小鼠上皮紧密连接通透性和促炎反应。

Am J Pathol. 2013 Mar;182(3):852-65. doi: 10.1016/j.ajpath.2012.11.035. Epub 2013 Jan 26.

The immunopathogenesis of Entamoeba histolytica.溶组织内阿米巴的免疫发病机制。

Exp Parasitol. 2010 Nov;126(3):366-80. doi: 10.1016/j.exppara.2010.03.005. Epub 2010 Mar 19.

Chemotaxis of Entamoeba histolytica towards the pro-inflammatory cytokine TNF is based on PI3K signalling, cytoskeleton reorganization and the Galactose/N-acetylgalactosamine lectin activity.溶组织内阿米巴对促炎细胞因子TNF的趋化作用基于磷脂酰肌醇-3激酶（PI3K）信号传导、细胞骨架重组和半乳糖/N-乙酰半乳糖胺凝集素活性。

Cell Microbiol. 2008 Aug;10(8):1676-86. doi: 10.1111/j.1462-5822.2008.01158.x. Epub 2008 Apr 16.

Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases.人类炎症性肠病中微生物群落失衡的分子系统发育特征

Proc Natl Acad Sci U S A. 2007 Aug 21;104(34):13780-5. doi: 10.1073/pnas.0706625104. Epub 2007 Aug 15.

Human tumor necrosis factor is a chemoattractant for the parasite Entamoeba histolytica.人类肿瘤坏死因子是溶组织内阿米巴寄生虫的一种趋化因子。

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The acetate switch.乙酸盐转换

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