Radhakrishnan Venkatraman, Kapoor Gauri, Arora Brijesh, Bansal Deepak, Vora Tushar, Prasad Maya, Chinnaswamy Girish, Laskar Siddharth, Agarwala Sandeep, Kaur Tanvir, Rath G K, Bakhshi Sameer
Department of Medical Oncology and Pediatric Oncology, Cancer Institute (W.I.A), Adyar, Chennai, India.
Department of Pediatric Hematology & Oncology, Rajiv Gandhi Cancer Institute & Research Center, Rohini, Sector 5, Delhi, 110085, India.
Indian J Pediatr. 2017 May;84(5):371-381. doi: 10.1007/s12098-017-2304-6. Epub 2017 Mar 30.
Pediatric Hodgkins lymphoma is a highly curable disease even in the developing world. Current treatment paradigms follow a risk and response based approach. The goal is to minimise treatment related short and long-term toxicity while maintaining excellent survival. A confirmed histopathological diagnosis and full staging work-up are essential prior to embarking on treatment and guidelines for these are provided in the text. All patients require combination chemotherapy while radiotherapy is usually reserved for a select subgroup depending on the protocol used. It is important to follow these patients for relapse in the first five years and life-long for late effects as most of them will be cured.
小儿霍奇金淋巴瘤即使在发展中国家也是一种治愈率很高的疾病。目前的治疗模式遵循基于风险和反应的方法。目标是在维持良好生存率的同时，将与治疗相关的短期和长期毒性降至最低。在开始治疗之前，确诊的组织病理学诊断和全面的分期检查至关重要，本文提供了相关指南。所有患者都需要联合化疗，而放疗通常根据所使用的方案保留给特定的亚组。对这些患者进行头五年的复发随访以及对晚期效应进行终身随访很重要，因为他们中的大多数将会治愈。
