用于治疗慢性疼痛和偏头痛的TRPM8拮抗剂的研发。
Development of TRPM8 Antagonists to Treat Chronic Pain and Migraine.
作者信息
Weyer Andy D, Lehto Sonya G
机构信息
Pacific University School of Physical Therapy, Hillsboro, OR 97123, USA.
One Amgen Center Dr, Thousand Oaks, CA 91320, USA.
出版信息
Pharmaceuticals (Basel). 2017 Mar 30;10(2):37. doi: 10.3390/ph10020037.
Abstract
A review. Development of pharmaceutical antagonists of transient receptor potential melastatin 8 (TRPM8) have been pursued for the treatment of chronic pain and migraine. This review focuses on the current state of this progress.
摘要
综述。为治疗慢性疼痛和偏头痛，人们一直在研发瞬时受体电位 melastatin 8（TRPM8）的药物拮抗剂。本综述聚焦于这一进展的当前状况。
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