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用于提高大鼠皮层在微波照射下局部温度估计准确性的多物理场与热响应模型

Multiphysics and Thermal Response Models to Improve Accuracy of Local Temperature Estimation in Rat Cortex under Microwave Exposure.

作者信息

Kodera Sachiko, Gomez-Tames Jose, Hirata Akimasa, Masuda Hiroshi, Arima Takuji, Watanabe Soichi

机构信息

Department of Electrical and Mechanical Engineering, Nagoya Institute of Technology, Nagoya 466-8555, Japan.

Department of Environmental Medicine, Kurume University School of Medicine, Fukuoka 830-0011, Japan.

出版信息

Int J Environ Res Public Health. 2017 Mar 30;14(4):358. doi: 10.3390/ijerph14040358.

DOI:10.3390/ijerph14040358
PMID:28358345
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5409559/
Abstract

The rapid development of wireless technology has led to widespread concerns regarding adverse human health effects caused by exposure to electromagnetic fields. Temperature elevation in biological bodies is an important factor that can adversely affect health. A thermophysiological model is desired to quantify microwave (MW) induced temperature elevations. In this study, parameters related to thermophysiological responses for MW exposures were estimated using an electromagnetic-thermodynamics simulation technique. To the authors' knowledge, this is the first study in which parameters related to regional cerebral blood flow in a rat model were extracted at a high degree of accuracy through experimental measurements for localized MW exposure at frequencies exceeding 6 GHz. The findings indicate that the improved modeling parameters yield computed results that match well with the measured quantities during and after exposure in rats. It is expected that the computational model will be helpful in estimating the temperature elevation in the rat brain at multiple observation points (that are difficult to measure simultaneously) and in explaining the physiological changes in the local cortex region.

摘要

无线技术的迅速发展引发了人们对暴露于电磁场对人体健康产生有害影响的广泛关注。生物体内的温度升高是一个会对健康产生不利影响的重要因素。需要一个热生理模型来量化微波(MW)引起的温度升高。在本研究中,使用电磁热力学模拟技术估计了与MW暴露的热生理反应相关的参数。据作者所知,这是第一项通过对频率超过6 GHz的局部MW暴露进行实验测量,以高精度提取大鼠模型中与局部脑血流相关参数的研究。研究结果表明,改进后的建模参数产生的计算结果与大鼠暴露期间和暴露后的测量值匹配良好。预计该计算模型将有助于估计大鼠大脑多个观察点(难以同时测量)的温度升高,并有助于解释局部皮质区域的生理变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e352/5409559/09c4b46de835/ijerph-14-00358-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e352/5409559/005e69cd4b1b/ijerph-14-00358-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e352/5409559/beb8bdd0a599/ijerph-14-00358-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e352/5409559/e2e09ad953d9/ijerph-14-00358-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e352/5409559/f2ae89283758/ijerph-14-00358-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e352/5409559/74565c503e2d/ijerph-14-00358-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e352/5409559/b3326ecf4940/ijerph-14-00358-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e352/5409559/09c4b46de835/ijerph-14-00358-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e352/5409559/005e69cd4b1b/ijerph-14-00358-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e352/5409559/beb8bdd0a599/ijerph-14-00358-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e352/5409559/e2e09ad953d9/ijerph-14-00358-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e352/5409559/f2ae89283758/ijerph-14-00358-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e352/5409559/74565c503e2d/ijerph-14-00358-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e352/5409559/b3326ecf4940/ijerph-14-00358-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e352/5409559/09c4b46de835/ijerph-14-00358-g007.jpg

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A Closer Look at the Thresholds of Thermal Damage: Workshop Report by an ICNIRP Task Group.深入探究热损伤阈值:国际非电离辐射防护委员会任务组的研讨会报告
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No Dynamic Changes in Blood-brain Barrier Permeability Occur in Developing Rats During Local Cortex Exposure to Microwaves.在发育中的大鼠局部皮层暴露于微波期间,血脑屏障通透性未发生动态变化。
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