Santos S, Le Lez M L, Arsène S, Pisella P J
Cabinet privé, 12, rue des Cytises, 37300 Joué-lès-Tours, France; Service ophtalmologie, 2, boulevard Tonnellé, 37000 Tours, France.
Service ophtalmologie, 2, boulevard Tonnellé, 37000 Tours, France.
J Fr Ophtalmol. 2017 Apr;40(4):285-296. doi: 10.1016/j.jfo.2016.12.009. Epub 2017 Mar 27.
Vitreoretinal lymphoma is a serious disease with highly varied clinical presentations. The goal of this work is to identify the various presentations (clinical, imaging) in order to improve screening for this disease.
We collected data of patients followed on our service for vitreoretinal lymphoma. The fundus exam, autofluorescence and angiography data were classified in order to identify signs, which might lead to earlier diagnosis of lymphoma.
The diagnosis of vitreoretinal lymphoma was confirmed by vitrectomy or cerebral biopsy for 12 patients (8 women and 4 men). Three clinical presentations were identified: no retinal involvement (2 patients), retinal infiltrate (4 patients) or acute retinal necrosis (3 patients). One patient had no imaging (deceased before it could be obtained), and two patients had uninterpretable imaging.
Vitreoretinal lymphoma remains a rare and under-diagnosed disease. The prognosis is related to early diagnosis. Multimodal imaging can help to diagnose early vitreoretinal lymphoma in some cases.
玻璃体视网膜淋巴瘤是一种临床表现高度多样的严重疾病。这项工作的目标是识别各种表现（临床、影像学），以改善对该疾病的筛查。
我们收集了在我们科室接受玻璃体视网膜淋巴瘤治疗的患者的数据。对眼底检查、自发荧光和血管造影数据进行分类，以识别可能有助于早期诊断淋巴瘤的体征。
12例患者（8例女性和4例男性）经玻璃体切除术或脑活检确诊为玻璃体视网膜淋巴瘤。确定了三种临床表现：无视网膜受累（2例患者）、视网膜浸润（4例患者）或急性视网膜坏死（3例患者）。1例患者未进行影像学检查（在可进行检查前死亡），2例患者的影像学检查结果无法解读。
玻璃体视网膜淋巴瘤仍然是一种罕见且诊断不足的疾病。预后与早期诊断有关。多模态成像在某些情况下有助于早期诊断玻璃体视网膜淋巴瘤。
