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本文引用的文献

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Phagocytosis: Hungry, Hungry Cells.吞噬作用：饥饿的细胞
Methods Mol Biol. 2017;1519:1-16. doi: 10.1007/978-1-4939-6581-6_1.
2
The binary toxin CDT enhances Clostridium difficile virulence by suppressing protective colonic eosinophilia.二元毒素 CDT 通过抑制保护性结肠嗜酸性粒细胞来增强艰难梭菌的毒力。
Nat Microbiol. 2016 Jul 11;1(8):16108. doi: 10.1038/nmicrobiol.2016.108.
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Eosinophils, probiotics, and the microbiome.嗜酸性粒细胞、益生菌与微生物群。
J Leukoc Biol. 2016 Nov;100(5):881-888. doi: 10.1189/jlb.3RI0416-202R. Epub 2016 Aug 22.
4
Microbiota-Regulated IL-25 Increases Eosinophil Number to Provide Protection during Clostridium difficile Infection.微生物群调节的白细胞介素-25增加嗜酸性粒细胞数量以在艰难梭菌感染期间提供保护。
Cell Rep. 2016 Jul 12;16(2):432-443. doi: 10.1016/j.celrep.2016.06.007. Epub 2016 Jun 23.
5
Isolation of Eosinophils from the Lamina Propria of the Murine Small Intestine.从小鼠小肠固有层分离嗜酸性粒细胞。
Methods Mol Biol. 2016;1422:213-21. doi: 10.1007/978-1-4939-3603-8_20.
6
A Simple, Reproducible, Inexpensive, Yet Old-Fashioned Method for Determining Phagocytic and Bactericidal Activities of Macrophages.一种用于测定巨噬细胞吞噬和杀菌活性的简单、可重复、廉价且传统的方法。
Yonsei Med J. 2016 Mar;57(2):283-90. doi: 10.3349/ymj.2016.57.2.283.
7
Eosinophil extracellular trap cell death-derived DNA traps: Their presence in secretions and functional attributes.嗜酸性粒细胞胞外诱捕细胞死亡衍生的DNA陷阱：它们在分泌物中的存在及功能特性。
J Allergy Clin Immunol. 2016 Jan;137(1):258-267. doi: 10.1016/j.jaci.2015.04.041. Epub 2015 Jun 9.
8
IL-1β in eosinophil-mediated small intestinal homeostasis and IgA production.白细胞介素-1β在嗜酸性粒细胞介导的小肠内环境稳定及免疫球蛋白A产生中的作用
Mucosal Immunol. 2015 Jul;8(4):930-42. doi: 10.1038/mi.2014.123. Epub 2015 Jan 7.
9
Interaction between Campylobacter and intestinal epithelial cells leads to a different proinflammatory response in human and porcine host.弯曲杆菌与肠道上皮细胞之间的相互作用在人和猪宿主中引发不同的促炎反应。
Vet Immunol Immunopathol. 2014 Nov 15;162(1-2):14-23. doi: 10.1016/j.vetimm.2014.09.003. Epub 2014 Sep 28.
10
Eosinophils promote generation and maintenance of immunoglobulin-A-expressing plasma cells and contribute to gut immune homeostasis.嗜酸性粒细胞促进分泌免疫球蛋白 A 的浆细胞的生成和维持，并有助于肠道免疫稳态。
Immunity. 2014 Apr 17;40(4):582-93. doi: 10.1016/j.immuni.2014.02.014.

一种评估嗜酸性粒细胞介导的益生菌罗伊氏乳杆菌摄取的流式细胞术方法。

A flow-cytometric method to evaluate eosinophil-mediated uptake of probiotic Lactobacillus reuteri.

作者信息

Kraemer Laura S, Brenner Todd A, Krumholz Julia O, Rosenberg Helene F

机构信息

Inflammation Immunobiology Section, Laboratory of Allergic Diseases, NIAID, National Institutes of Health, Bethesda, MD 20892, United States.

Inflammation Immunobiology Section, Laboratory of Allergic Diseases, NIAID, National Institutes of Health, Bethesda, MD 20892, United States.

出版信息

J Microbiol Methods. 2017 Jun;137:19-24. doi: 10.1016/j.mimet.2017.03.015. Epub 2017 Mar 27.

DOI:10.1016/j.mimet.2017.03.015
PMID:28359737
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5443408/
Abstract

Eosinophils are resident leukocytes of gut mucosa. Here we present a combined flow cytometric-antibiotic protection assay to identify mouse eosinophils capable of bacterial uptake, specifically, Gram-positive Lactobacillus reuteri, in studies performed ex vivo. The assay may be adapted for use in vivo.

摘要

嗜酸性粒细胞是肠道黏膜的常驻白细胞。在此，我们展示了一种流式细胞术与抗生素保护试验相结合的方法，用于在体外研究中鉴定能够摄取细菌（具体为革兰氏阳性的罗伊氏乳杆菌）的小鼠嗜酸性粒细胞。该试验可适用于体内研究。