Gumulak Rene, Lucanova Lucia Casnocha, Zibolen Mirko
Department of Neonatology, Jessenius Medical Faculty in Martin, Comenius University in Bratislava and University Hospital in Martin, Slovak Republic.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2017 Jun;161(2):128-133. doi: 10.5507/bp.2017.012. Epub 2017 Mar 30.
Near-infrared spectroscopy (NIRS) is a technology capable of non-invasive, continuous measuring of regional tissue oxygen saturation (StO). StO represents a state of hemodynamic stability, which is influenced by many factors. Extensive research has been done in the field of measuring StO of various organs. The current clinical availability of several NIRS-based devices reflects an important development in prevention, detection and correction of discrepancy in oxygen delivery to the brain and vital organs. Managing cerebral ischemia remains a significant issue in the neonatal intensive care units (NICU). Cerebral tissue oxygenation (cStO) and cerebral fractional tissue extraction (cFTOE) are reported in a large number of clinical studies. This review provides a summary of the concept of function, current variability of NIRS-based devices used in neonatology, clinical applications in continuous cStO monitoring, limitations, disadvantages, and the potential of current technology.
近红外光谱技术（NIRS）是一种能够对局部组织氧饱和度（StO）进行无创、连续测量的技术。StO代表一种血流动力学稳定状态，它受多种因素影响。在测量各器官StO领域已开展了广泛研究。目前几款基于NIRS的设备在临床上的应用反映出在预防、检测和纠正大脑及重要器官氧输送差异方面的一项重要进展。在新生儿重症监护病房（NICU）中，处理脑缺血仍然是一个重大问题。大量临床研究报告了脑组织氧合（cStO）和脑部分组织摄取率（cFTOE）。本综述总结了功能概念、新生儿学中使用的基于NIRS的设备当前的变异性、连续cStO监测的临床应用、局限性、缺点以及当前技术的潜力。
