Gu Gangfeng, Jiang Junyao, Zheng Bo, Li Yan, Luo Yuding, Pu Yunhai, Wang Jian
Department of Neurology, Ya'an People's Hospital, Ya'an, 625000, China.
Chengdu Yunweikang Medical Treatment Technology Co., Ltd, Chengdu, 610000, China.
J Clin Monit Comput. 2025 Apr;39(2):283-289. doi: 10.1007/s10877-024-01244-0. Epub 2024 Nov 25.
Regional cerebral oxygen saturation (rSO) may vary in healthy individuals with different characteristics. Therefore, this study aimed to explore rSO in a healthy population of western Sichuan. This cross-sectional study enrolled healthy volunteers from the Health Management Center and Inpatient Department of Ya'an People's Hospital, Ya'an Vocational and Technical College, Ya'an Geriatric University, and Liziping Yi Township in Shimian County, Ya'an City, Sichuan Province. Brain rSO was measured by near-infrared spectroscopy (NIRS) between January 2020 and December 2022. A total of 661 volunteers were enrolled, with a mean age of 28.3 ± 23.1 years old and 276 males. There was significantly higher rSO of the left brain in females (63.46 ± 3.01 vs. 63.17 ± 2.90, P = 0.015), males (63.91 ± 3.54 vs. 63.42 ± 3.32, P = 0.002), Han (65.10 ± 3.67 vs. 64.38 ± 3.43, P < 0.001), and volunteers aged 14-59 years (P < 0.05) compared with the right brain. Volunteers with Han ethnicity had significantly higher rSO than those with Yi ethnicity (64.65 ± 3.29 vs. 62.68 ± 3.66, P < 0.001). Volunteers with past illness had significantly lower rSO than those without past illness (62.41 ± 3.06 vs. 62.68 ± 3.66, P = 0.021). Pearson correlation analysis showed a significantly negative correlation of rSO with age, ethics, past illness, and body mass index (BMI) but a significantly positive correlation with head circumference and height (all P < 0.05). The rSO values in the left brain are significantly higher than in the right brain. Sex, ethnicity, age, BMI, and past illness are closely related to rSO values in the healthy population.
局部脑氧饱和度（rSO）在具有不同特征的健康个体中可能会有所不同。因此，本研究旨在探索川西健康人群的rSO。这项横断面研究招募了来自雅安市人民医院健康管理中心、雅安市职业技术学院、雅安老年大学以及四川省雅安市石棉县栗子坪彝族乡住院部的健康志愿者。在2020年1月至2022年12月期间，通过近红外光谱（NIRS）测量脑rSO。共招募了661名志愿者，平均年龄为28.3±23.1岁，男性276名。女性（63.46±3.01 vs. 63.17±2.90，P = 0.015）、男性（63.91±3.54 vs. 63.42±3.32，P = 0.002）、汉族（65.10±3.67 vs. 64.38±3.43，P < 0.001）以及14至59岁的志愿者（P < 0.05）的左脑rSO均显著高于右脑。汉族志愿者的rSO显著高于彝族志愿者（64.65±3.29 vs. 62.68±3.66，P < 0.001）。有既往病史的志愿者的rSO显著低于无既往病史的志愿者（62.41±3.06 vs. 62.68±3.66，P = 0.021）。Pearson相关性分析显示，rSO与年龄、种族、既往病史和体重指数（BMI）呈显著负相关，但与头围和身高呈显著正相关（均P < 0.05）。左脑的rSO值显著高于右脑。性别、种族、年龄、BMI和既往病史与健康人群的rSO值密切相关。
