肉毒杆菌毒素在偏头痛治疗中的应用
Botulinum Toxin in Migraine Treatment.
作者信息
Ilgaz Aydinlar Elif, Yalinay Dikmen Pınar, Sağduyu Kocaman Ayşe
机构信息
Acıbadem University, Medical Faculty, Department of Neurology, İstanbul, Turkey.
出版信息
Noro Psikiyatr Ars. 2013 Aug;50(Suppl 1):S36-S40. doi: 10.4274/npa.y7198. Epub 2013 Aug 1.
Abstract
Since botulinum toxin might have a therapeutic effect on pain, many studies investigating the efficiency of botulinum toxin in headache treatment have been done. The most satisfying results were achieved by botulinum toxin type A (BoNT/A) in the treatment of chronic migraine. In this paper, we reviewed the clinical effectiveness of BoNT/A in migraine and included our clinical experience. In our ongoing pilot study, where we have repeated BoNT/A injections every 12 weeks, The difference in the Migraine Disability Assessment (MIDAS) scores between the first and the second injections was 61.1%; and between the first and the 3rd injections was found to be 65.72%.
摘要
由于肉毒杆菌毒素可能对疼痛具有治疗作用，因此已经开展了许多研究来调查肉毒杆菌毒素在头痛治疗中的效果。A型肉毒杆菌毒素（BoNT/A）在慢性偏头痛治疗中取得了最令人满意的结果。在本文中，我们回顾了BoNT/A在偏头痛治疗中的临床疗效，并纳入了我们的临床经验。在我们正在进行的初步研究中，我们每12周重复注射BoNT/A，首次注射与第二次注射之间的偏头痛残疾评估（MIDAS）评分差异为61.1%；首次注射与第三次注射之间的差异为65.72%。
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