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Curr Pain Headache Rep. 2011 Oct;15(5):336-8. doi: 10.1007/s11916-011-0202-6.
Chronic migraine headache remains an exceedingly difficult entity to manage. Treatment of chronic migraine headache with onabotulinumtoxinA has recently been shown to be effective in reducing the severity and frequency of chronic migraine headache, in the PREEMPT trials, a landmark achievement. However, the studies use a primarily fixed dose and site approach to treatment, allowing some individualized injections. However, the authors do not address the issue of myofascial trigger points as potential triggers of migraine that could be inactivated using onabotulinumtoxinA, despite several studies that support the role of myofascial trigger points in initiating some migraine headaches.
慢性偏头痛仍然是一种极难治疗的疾病。在 PREEMPT 试验中，肉毒毒素 A 治疗慢性偏头痛头痛的疗效已被证明可以有效减轻慢性偏头痛头痛的严重程度和频率，这是一项具有里程碑意义的成就。然而，这些研究主要采用固定剂量和固定部位的治疗方法，只允许进行一些个体化的注射。然而，作者并没有提到肌筋膜触发点作为偏头痛潜在触发点的问题，尽管有几项研究支持肌筋膜触发点在引发某些偏头痛方面的作用。
