Saribacak Ali, Altinbaş Kürşat, Yilmaz Hasan, Özkan Alp, Özkan Levend, Oral Timuçin
Konak Hospital, Clinic of Urology, Kocaeli, Turkey.
Çanakkale Onsekiz Mart University Faculty of Medicine, Department of Psychiatry, Çanakkale, Turkey.
Noro Psikiyatr Ars. 2014 Sep;51(3):263-266. doi: 10.4274/npa.y6889. Epub 2014 Sep 1.
Overactive bladder (OAB) is generally characterized by urinary urgency with or without incontinence and increased frequency of voiding and nocturia. Although animal studies have demonstrated the relationship between defective serotonergic neurotransmission and OAB, its etiology is still unclarified. Temperament profiles are hypothesized to be related with serotonergic activity and are studied in many psychosomatic disorders. Thus, we assume that OAB is related with a certain type of temperament.
29 patients, who were admitted to the urology outpatient clinic at Kocaeli University and clinically diagnosed with OAB syndrome, were recruited for the study. Temperament profiles were evaluated with the Temperament Evaluation of Memphis Pisa Paris and San Diego Autoquestionnaire (TEMPS-A). Depressive, hyperthymic, cyclothymic, anxious and irritable temperament scores in patients were compared with those in 25 healthy controls.
Patient and control groups were similar in terms of age (p=.65), sex (p=.64) and educational level (p=.90). Anxious temperament scores were higher (p=.02) and hyperthymic temperament scores were lower (p=.02) in patients with OAB compared to controls. Depressive, cyclothymic and irritable temperament scores were similar in both groups. There was no significant differences between men and women in both groups in terms of different temperament profile scores.
Hypothetically, there might be an association between anxious temperament and OAB syndrome reflecting serotonergic dysfunction. However, OAB syndrome must be considered from the aspect of the interdependence of psychosomatic implications in a narrow sense and psychosomatic dimensions due to the psychological predisposition in the individual case.
膀胱过度活动症（OAB）的一般特征是伴有或不伴有尿失禁的尿急、排尿频率增加和夜尿症。尽管动物研究已经证明了血清素能神经传递缺陷与OAB之间的关系，但其病因仍未明确。气质特征被假设与血清素能活动有关，并在许多心身疾病中得到研究。因此，我们假设OAB与某种类型的气质有关。
招募了29名在科贾埃利大学泌尿外科门诊就诊并临床诊断为OAB综合征的患者进行研究。使用孟菲斯、比萨、巴黎和圣地亚哥气质自评问卷（TEMPS-A）评估气质特征。将患者的抑郁、轻躁狂、环性心境、焦虑和易怒气质得分与25名健康对照者的得分进行比较。
患者组和对照组在年龄（p = 0.65）、性别（p = 0.64）和教育水平（p = 0.90）方面相似。与对照组相比，OAB患者的焦虑气质得分更高（p = 0.02），轻躁狂气质得分更低（p = 0.02）。两组的抑郁、环性心境和易怒气质得分相似。两组中男性和女性在不同气质特征得分方面没有显著差异。
假设焦虑气质与反映血清素能功能障碍的OAB综合征之间可能存在关联。然而，由于个体病例中的心理易感性，必须从狭义的心身影响和心身维度的相互依存方面考虑OAB综合征。
