Gözübatik-Çelik Gökçen, Uygunoğlu Uğur, Uludüz Derya, Atahan Ersan, Müsellim Benan, Saip Sabahattin, Siva Aksel
Department of Neurology, İstanbul University Cerrahpaşa Faculty of Medicine, İstanbul, Turkey.
Department of Pulmonology, İstanbul University Cerrahpaşa Faculty of Medicine, İstanbul, Turkey.
Noro Psikiyatr Ars. 2015 Mar;52(1):102-106. doi: 10.5152/npa.2015.7318. Epub 2015 Mar 1.
Sarcoidosis is an inflammatory multisystem disorder, affecting many systems such as lung, lymph nodes, skin and eye involvement. Nervous system involvement is often seen in 5-15% of patients with systemic sarcoidosis in the first two years. Preceding to systemic involvement the initial symptom as neurological complaints has been rarely reported. Lacking of any specific, clinical and / or radiological findings for neurosarcoidosis in these cases, it could be difficult to make an accurate diagnosis and histopathological evaluation may be required. Due to rarity and complexity diagnosis of the neurosarcoidosis, in this study, clinical, radiological and / or histopathological features, treatment modalities of the 7 neurosarcoidosis patients to be presented with detailed investigations of different neurological symptoms were evaluated.
结节病是一种炎症性多系统疾病,可累及许多系统,如肺部、淋巴结、皮肤和眼部。在系统性结节病患者中,5%-15%在发病的头两年常出现神经系统受累。在系统性受累之前,以神经症状为初始症状的情况鲜有报道。由于这些病例缺乏任何针对神经结节病的特异性临床和/或放射学表现,因此可能难以做出准确诊断,可能需要进行组织病理学评估。由于神经结节病的诊断罕见且复杂,本研究对7例表现出不同神经症状并经过详细检查的神经结节病患者的临床、放射学和/或组织病理学特征及治疗方式进行了评估。