Cumine Florimond, Zhou Shengze, Tuttle Tell, Murphy John A
WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow G1 1XL, U.K.
Org Biomol Chem. 2017 Apr 11;15(15):3324-3336. doi: 10.1039/c7ob00036g.
Several diketopiperazines have been shown to promote carbon-carbon coupling between benzene and aryl halides in the presence of potassium tert-butoxide and without the assistance of a transition metal catalyst. The structure of the diketopiperazine has an influence on its reductive potential and can help to promote the coupling of the more challenging aryl bromides with benzene.
已表明，在叔丁醇钾存在且无过渡金属催化剂辅助的情况下，几种二酮哌嗪可促进苯与芳基卤化物之间的碳 - 碳偶联。二酮哌嗪的结构对其还原电位有影响，并且有助于促进更具挑战性的芳基溴化物与苯的偶联。
