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葡萄球菌肠毒素和肠毒素样毒素,特别提及乳制品:概述。

Staphylococcal enterotoxins and enterotoxin-like toxins with special reference to dairy products: An overview.

机构信息

a Department of Food Science and Agricultural Chemistry, Macdonald-Stewart Building , McGill University, Macdonald Campus , Sainte-Anne-de-Bellevue , Canada.

出版信息

Crit Rev Food Sci Nutr. 2018;58(12):1943-1970. doi: 10.1080/10408398.2017.1289149. Epub 2017 Jun 2.

Abstract

Staphylococcal Enterotoxins (SEs) have been raising health concerns for food safety due to their association with staphylococcal foodborne poisoning (SFP). As superantigens, they also cause the life threatening toxic shock syndrome (TSS), the transmission of which via food cannot be ruled out despite the lack of epidemiological evidence. To date, at least 23 of these exotoxins are known and separated into SEs and Staphylococcal Enterotoxin-like (SEl) depending on whether or not they invoke emesis. This work presents an up-to-date overview on the presently known SEs/SEls from the perspective of their classification, pathogenesis, and genetic organisation. The incidence of these toxins in dairy products, the risk this poses to the public health, and possible control means are also reviewed.

摘要

葡萄球菌肠毒素(SEs)因其与葡萄球菌食源性中毒(SFP)有关而引起了人们对食品安全的健康关注。作为超抗原,它们还会导致危及生命的中毒性休克综合征(TSS),尽管缺乏流行病学证据,但不能排除通过食物传播的可能性。迄今为止,已知至少有 23 种此类外毒素,并根据它们是否引起呕吐分为 SEs 和葡萄球菌肠毒素样(SEl)。这项工作从分类、发病机制和遗传组织的角度对目前已知的 SEs/SEls 进行了最新概述。还回顾了这些毒素在乳制品中的发生率、对公众健康构成的风险以及可能的控制手段。

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