Evan Meredith, Risher Kathryn, Zungu Nompumelelo, Shisana Olive, Moyo Sizulu, Celentano David D, Maughan-Brown Brendan, Rehle Thomas M
Department of Anthropology, York University, Toronto, Canada.
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
J Int AIDS Soc. 2016 Dec 26;19(1):21310. doi: 10.7448/IAS.19.1.21310.
Age-disparate sex has long been considered a factor that increases HIV risk for young women in South Africa. However, recent studies from specific regions in South Africa have found conflicting evidence. Few studies have assessed the association between age-disparate partnerships (those involving an age gap of 5 years or more) and HIV risk at the national level. This study investigates the relationship between age-disparate sex and HIV status among young women aged 15-24 in South Africa.
Nationally representative weighted data from the 2002, 2005, 2008, and 2012 South African National HIV Surveys were analysed for young women aged 15-24 years using bivariate analyses and multiple logistic regressions.
After conducting multiple logistic regression analyses and controlling for confounders, young women with age-disparate partners had greater odds of being HIV positive in every survey year: 2002 (aOR = 1.74, 95%CI: 0.81-3.76, p = 0.16); 2005 (aOR = 2.11, 95%CI: 1.22-3.66, p < 0.01); 2008 (aOR = 2.02, 95%CI: 1.24-3.29, p < 0.01); 2012 (aOR = 1.53, 95%CI: 0.92-2.54, p < 0.1). The odds of being HIV positive increased for each year increase in their male partner's age in 2002 (aOR = 1.10, 95%CI: 0.98-1.22, p = 0.11), 2005 (aOR = 1.10, 95%CI: 1.03-1.17, p < 0.01), 2008 (aOR = 1.08, 95%CI: 1.01-1.15, p < 0.05), and 2012 (aOR = 1.08, 95%CI: 1.01-1.16, p < 0.05). Findings were statistically significant (p < 0.1) for the years 2005, 2008, and 2012.
Our findings suggest that age-disparate sex continues to be a risk factor for young women aged 15-24 in South Africa at a national level. These results may reflect variation in HIV risk at the national level compared to the differing results from recent studies in a demographic surveillance system and trial contexts. In light of recent contradictory study results, further research is required on the relationship between age-disparate sex and HIV for a more nuanced understanding of young women's HIV risk.
长期以来,年龄差距较大的异性性行为一直被视为增加南非年轻女性感染艾滋病毒风险的一个因素。然而,南非特定地区最近的研究发现了相互矛盾的证据。很少有研究在国家层面评估年龄差距较大的性伴侣关系(年龄差距在5岁及以上)与艾滋病毒感染风险之间的关联。本研究调查了南非15至24岁年轻女性中年龄差距较大的异性性行为与艾滋病毒感染状况之间的关系。
利用双变量分析和多元逻辑回归,对2002年、2005年、2008年和2012年南非全国艾滋病毒调查中具有全国代表性的加权数据进行分析,研究对象为15至24岁的年轻女性。
在进行多元逻辑回归分析并控制混杂因素后,在每个调查年份,有年龄差距较大性伴侣的年轻女性感染艾滋病毒呈阳性的几率更高:2002年(调整后的比值比[aOR]=1.74,95%置信区间[CI]:0.81 - 3.76,p=0.16);2005年(aOR=2.11,95%CI:1.22 - 3.66,p<0.01);2008年(aOR=2.02,95%CI:1.24 - 3.29,p<0.01);2012年(aOR=1.53,95%CI:0.92 - 2.54,p<0.1)。在2002年(aOR=1.10,95%CI:0.98 - 1.22,p=0.11)、2005年(aOR=1.10,95%CI:1.03 - 1.17,p<0.01)、2008年(aOR=1.08,95%CI:1.01 - 1.15,p<0.05)和2012年(aOR=1.08,95%CI:1.01 - 1.16,p<0.05),随着男性伴侣年龄每增加一岁,感染艾滋病毒呈阳性的几率都会增加。2005年、2008年和2012年的研究结果具有统计学意义(p<0.1)。
我们的研究结果表明,在国家层面,年龄差距较大的异性性行为仍然是南非15至24岁年轻女性感染艾滋病毒的一个风险因素。与人口监测系统和试验背景下近期研究得出的不同结果相比,这些结果可能反映了国家层面艾滋病毒感染风险的差异。鉴于近期相互矛盾的研究结果,需要进一步研究年龄差距较大的异性性行为与艾滋病毒之间的关系,以便更细致地了解年轻女性的艾滋病毒感染风险。