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中国人群中EZSCAN参数在糖尿病筛查中的价值

Value of EZSCAN parameters for diabetes screening in Chinese.

作者信息

Lin Yanhui, Chen Zhiheng, Guo Xu, Deng Yulin

机构信息

Department of Health Management, Third Xiangya Hospital, Central South University, Changsha, Hunan, China.

Department of Health Management, Third Xiangya Hospital, Central South University, Changsha, Hunan, China.

出版信息

Med Clin (Barc). 2017 May 23;148(10):444-448. doi: 10.1016/j.medcli.2016.11.037. Epub 2017 Mar 31.

DOI:10.1016/j.medcli.2016.11.037
PMID:28366245
Abstract

OBJECTIVE

To study the parameters of EZSCAN as a screening tool for diabetes in Chinese.

METHODS

A total of 6,270 subjects participated in the study. All subjects underwent tests of EZSCAN, fasting plasma glucose (FPG), oral glucose tolerance test and HbA.

RESULTS

  1. All subjects were divided into 4 groups: the normal group, sugar metabolic abnormalities as low-risk group, middle-risk group and high-risk group. The difference of diabetes incidence among the 4 groups was statistically significant. With the increase of EZSCAN score, the prevalence of diabetes increased significantly. But there is no statistically difference between the low-risk group and the middle-risk group. 2. After adjustment for other variables, there is significantly positive relationship among EZSCAN risk score and the risk of diabetes. Meanwhile there is no statistically difference between the low-risk group and the middle-risk group. 3. The cut-off point of EZSCAN for diabetes was 44.5% with the sensitivity was 73.2% which was higher than of FPG and HbA.

CONCLUSION

As EZSCAN-diabetes risk score increases, the risk of diabetes increases. EZSCAN can be used as a tool for screening for diabetes. At the best screening diabetes cut-off point value 44.5%, the sensitivity is higher than traditional method of FPG and HbA.

摘要

目的

研究EZSCAN作为中国人群糖尿病筛查工具的参数。

方法

共有6270名受试者参与本研究。所有受试者均接受了EZSCAN、空腹血糖(FPG)、口服葡萄糖耐量试验及糖化血红蛋白(HbA)检测。

结果

  1. 所有受试者分为4组:正常组、糖代谢异常低危组、中危组和高危组。4组间糖尿病发病率差异有统计学意义。随着EZSCAN评分升高,糖尿病患病率显著增加。但低危组与中危组之间无统计学差异。2. 调整其他变量后,EZSCAN风险评分与糖尿病风险呈显著正相关。同时,低危组与中危组之间无统计学差异。3. EZSCAN诊断糖尿病的切点为44.5%,其灵敏度为73.2%,高于FPG和HbA。

结论

随着EZSCAN糖尿病风险评分升高,糖尿病风险增加。EZSCAN可作为糖尿病筛查工具。在最佳筛查糖尿病切点值44.5%时,其灵敏度高于传统的FPG和HbA检测方法。

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