Evidence that prolonged alpha-MSH infusion enhances the steroidogenic capacity of rat adrenal zona glomerulosa in vivo.
作者信息
Mazzocchi G, Malendowicz L K, Gottardo G, Nussdorfer G G
机构信息
Department of Anatomy, University of Padua, Italy.
出版信息
J Steroid Biochem. 1988 Apr;29(4):441-2. doi: 10.1016/0022-4731(88)90255-5.
PMID:2836657
Abstract
Prolonged infusion with 120 micrograms/kg/day alpha-MSH significantly increased basal plasma level of aldosterone in the rat, as well as raised the acute aldosterone response to a bolus administration of a high dose of ACTH or angiotensin II. These findings suggest that chronic alpha-MSH treatment stimulates the steroidogenic capacity of rat zona glomerulosa.
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