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卵巢高钙血症型小细胞癌(SCCOHT):体外受精(IVF)后的罕见病例。

Small cell carcinoma of the ovary hypercalcemic type (SCCOHT): A rare case after in vitro fertilization (IVF).

作者信息

Ghazi Ahmed, Ayaz Aqueela, Hamid Tahira, Farooq Mian Usman, Islam Nikita

机构信息

Ahmed Ghazi, MBBS, Saudi board. Department of Gyne Oncology, King Abdullah Medical City (KAMC-HC), Makkah, Saudi Arabia.

Aqueela Ayaz, MBBS, FCPS. Department of Gyne Oncology, King Abdullah Medical City (KAMC-HC), Makkah, Saudi Arabia.

出版信息

Pak J Med Sci. 2017 Jan-Feb;33(1):241-244. doi: 10.12669/pjms.331.11634.

Abstract

Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a very rare and lethal tumor, mostly affecting young women, with aggressive clinical course. It has a worse prognosis in younger women and most of them died within two years of diagnosis. We are reporting a unique case of SCCOHT in a 35 years old, nulliparous lady with primary infertility in which symptomatic hypercalcemia was a presenting feature of her cancer. She was completely healthy before third cycle of IVF. Within two months of her third IVF cycle, she developed SCCOHT with a very rapid and aggressive course of disease and fatal outcome. Patient died within one month of her first symptom presentation (3 months after IVF cycle).

摘要

卵巢小细胞癌高钙血症型(SCCOHT)是一种非常罕见且致命的肿瘤,主要影响年轻女性,临床病程侵袭性强。年轻女性的预后更差,她们中的大多数在诊断后两年内死亡。我们报告了一例独特的SCCOHT病例,患者为一名35岁、未生育、原发性不孕的女性,其癌症的首发症状为症状性高钙血症。在第三次体外受精周期之前,她完全健康。在第三次体外受精周期后的两个月内,她患上了SCCOHT,疾病进展非常迅速且具有侵袭性,最终导致死亡。患者在出现首个症状后的一个月内(体外受精周期后3个月)死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482d/5368318/b370d2d8abad/PJMS-33-241-g001.jpg

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