Ghazi Ahmed, Ayaz Aqueela, Hamid Tahira, Farooq Mian Usman, Islam Nikita
Ahmed Ghazi, MBBS, Saudi board. Department of Gyne Oncology, King Abdullah Medical City (KAMC-HC), Makkah, Saudi Arabia.
Aqueela Ayaz, MBBS, FCPS. Department of Gyne Oncology, King Abdullah Medical City (KAMC-HC), Makkah, Saudi Arabia.
Pak J Med Sci. 2017 Jan-Feb;33(1):241-244. doi: 10.12669/pjms.331.11634.
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a very rare and lethal tumor, mostly affecting young women, with aggressive clinical course. It has a worse prognosis in younger women and most of them died within two years of diagnosis. We are reporting a unique case of SCCOHT in a 35 years old, nulliparous lady with primary infertility in which symptomatic hypercalcemia was a presenting feature of her cancer. She was completely healthy before third cycle of IVF. Within two months of her third IVF cycle, she developed SCCOHT with a very rapid and aggressive course of disease and fatal outcome. Patient died within one month of her first symptom presentation (3 months after IVF cycle).
卵巢小细胞癌高钙血症型(SCCOHT)是一种非常罕见且致命的肿瘤,主要影响年轻女性,临床病程侵袭性强。年轻女性的预后更差,她们中的大多数在诊断后两年内死亡。我们报告了一例独特的SCCOHT病例,患者为一名35岁、未生育、原发性不孕的女性,其癌症的首发症状为症状性高钙血症。在第三次体外受精周期之前,她完全健康。在第三次体外受精周期后的两个月内,她患上了SCCOHT,疾病进展非常迅速且具有侵袭性,最终导致死亡。患者在出现首个症状后的一个月内(体外受精周期后3个月)死亡。