Saylany Lua, Ellepola Hasthika, Broom Elisha
Obstetrics and Gynecology, Logan Hospital, Logan, AUS.
Maternal-Fetal Medicine, Logan Hospital, Logan, AUS.
Cureus. 2024 Mar 6;16(3):e55696. doi: 10.7759/cureus.55696. eCollection 2024 Mar.
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a rare form of aggressive ovarian malignancy linked with mutations in the SMARCA4 gene. This disease predominantly affects young women within the first five decades of life and is associated with poor overall long-term survival, particularly when diagnosed in the advanced stage of the disease. Due to the low incidence of the condition and limited literature, current clinical decision-making is based on a small number of case series and case reports. We present an extremely rare case of SCCOHT diagnosed in a young female during her third trimester of pregnancy, requiring preterm delivery via cesarean section with simultaneous unilateral oophorectomy and salpingectomy.
卵巢高钙血症型小细胞癌(SCCOHT)是一种罕见的侵袭性卵巢恶性肿瘤,与SMARCA4基因的突变有关。这种疾病主要影响50岁前的年轻女性,且总体长期生存率较低,尤其是在疾病晚期被诊断出来时。由于该病发病率低且文献有限,目前的临床决策是基于少数病例系列和病例报告。我们报告了一例极为罕见的SCCOHT病例,该病例发生在一名年轻女性妊娠晚期,需要通过剖宫产进行早产,同时进行单侧卵巢切除术和输卵管切除术。