Snyder Alyson, Schiechert Rachel A, Zaiac Martin N
Traditional Rotating Intern, Broward Health Medical Center, Fort Lauderdale, Florida.
Hollywood Dermatology & Cosmetic Specialists, Hollywood, Florida.
J Clin Aesthet Dermatol. 2017 Feb;10(2):57-58. Epub 2017 Feb 1.
A 47-year-old woman presented with hyperpigmented patches on her upper extremities. The patient had begun using a topical estrogen cream in the affected areas prior to noticing the hyperpigmentation. A diagnosis of melasma secondary to topical estrogen cream was made. While systemic hormones are a well-documented trigger for the development of melasma, this case represents the first report of melasma associated with topical estrogens. Topical estrogens are frequently prescribed to postmenopausal women for skin rejuvenation. Melasma should be discussed as a potential side effect of systemic as well as topical estrogen preparations.
一名47岁女性因上肢出现色素沉着斑前来就诊。该患者在注意到色素沉着之前就已开始在受影响区域使用外用雌激素乳膏。诊断为外用雌激素乳膏继发的黄褐斑。虽然全身性激素是导致黄褐斑发生的一个有充分记录的诱因，但该病例是与外用雌激素相关的黄褐斑的首例报告。外用雌激素经常被开给绝经后女性用于皮肤年轻化。应将黄褐斑作为全身性以及外用雌激素制剂的一种潜在副作用进行讨论。
