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肾上腺素混合物用于肌间沟阻滞对全身麻醉下沙滩椅位术后血流动力学变化的影响:一项回顾性研究

Effect of an epinephrine mixture for interscalene block on hemodynamic changes after the beach chair position under general anesthesia: a retrospective study.

作者信息

Kim Bum-June, Lim Chae-Seong, Hong Boo-Hwi, Lee Ji-Yong, Lee Sun-Yeul, Lee Jung-Un, Kim Yoon-Hee, Lee Won-Hyung, Yoon Seok-Hwa

机构信息

Department of Anesthesiology and Pain Medicine, Chungnam National University Hospital, Daejeon, Korea.

出版信息

Korean J Anesthesiol. 2017 Apr;70(2):171-176. doi: 10.4097/kjae.2017.70.2.171. Epub 2017 Jan 12.

Abstract

BACKGROUND

The beach chair position (BCP) can cause significant hypotension. Epinephrine is used to prolong the duration of local anesthetics; it is also absorbed into blood and can exert systemic effects. This study determined the effects of epinephrine mixed with ropivacaine for an interscalene block (ISB) on hemodynamic changes related to BCP.

METHODS

Patient data collected from March 2013 to August 2014 were used retrospectively. We divided the patients into three groups: 1) ISB only, 2) I+G (general anesthesia after ISB without epinephrine), and 3) I+E+G (general anesthesia after ISB with epinephrine). Mean blood pressure (MBP) and heart rate (HR) were measured for 30 minutes at 5-minute intervals.

RESULTS

The study analyzed data from 431 patients. MBP tended to decrease gradually in the groups I+G and I+E+G. There were significant differences in MBP between the groups I+G and I, and between the groups I+G and I+E+G. Group I+E+G showed a significant increase in HR compared with the other two groups.

CONCLUSIONS

ISB with an epinephrine mixture did not prevent hypotension caused by the BCP after general anesthesia. HR increased only in response to the epinephrine mixture. A well-planned prospective study is required to compare hemodynamic changes in that context.

摘要

背景

沙滩椅位(BCP)可导致显著的低血压。肾上腺素用于延长局部麻醉药的作用时间;它也会被吸收进入血液并产生全身效应。本研究确定了肾上腺素与罗哌卡因混合用于肌间沟阻滞(ISB)对与BCP相关的血流动力学变化的影响。

方法

回顾性分析2013年3月至2014年8月收集的患者数据。我们将患者分为三组:1)单纯ISB组,2)I+G组(ISB后无肾上腺素的全身麻醉),3)I+E+G组(ISB后有肾上腺素的全身麻醉)。每隔5分钟测量平均血压(MBP)和心率(HR),持续30分钟。

结果

该研究分析了431例患者的数据。I+G组和I+E+G组的MBP有逐渐下降的趋势。I+G组与I组之间以及I+G组与I+E+G组之间的MBP存在显著差异。与其他两组相比,I+E+G组的HR显著升高。

结论

全身麻醉后,含肾上腺素混合物的ISB不能预防BCP引起的低血压。仅在使用肾上腺素混合物后HR升高。需要进行精心设计的前瞻性研究来比较在这种情况下的血流动力学变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a48/5370310/b53c9ad6b622/kjae-70-171-g001.jpg

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