Chacon-Cruz Enrique, Alvelais-Palacios Jorge Arturo, Rodriguez-Valencia Jaime Alfonso, Lopatynsky-Reyes Erika Zoe, Volker-Soberanes Maria Luisa, Rivas-Landeros Rosa Maria
Department of Pediatrics, Hospital General de Tijuana, Tijuana, BC, Mexico.
School of Medicine, Universidad Autonoma de Baja California, CISALUD Campus, Tecate, BC, Mexico.
Case Rep Infect Dis. 2017;2017:6132857. doi: 10.1155/2017/6132857. Epub 2017 Mar 6.
Neonatal conjunctivitis is usually associated with vagina's infection by sp., , and/or other bacteria during delivery. Meningococcal neonatal conjunctivitis is an extremely rare disease. We report a case of neonatal meningococcal sepsis/conjunctivitis and asymptomatic carriage of from both parents (vagina and nasopharynx). As part of our active surveillance for meningococcal disease at the Tijuana General Hospital (TGH), Mexico, we identified a 3-day-old newborn with meningococcal conjunctivitis and sepsis. The patient had a one-day history of conjunctivitis and poor feeding. Clinical examination confirmed profuse purulent conjunctival discharge, as well as clinical signs and laboratory findings suggestive of bacteraemia. Gram stain from conjunctival exudate revealed intracellular Gram negative diplococci; we presumed the baby had gonorrheal conjunctivitis; however, serogroup Y, was isolated both from conjunctival exudate and blood. Additionally, isolation of serogroup Y, was obtained from mother's vagina and both parents' nasopharynx. The baby was treated with 7 days of IV ceftriaxone and discharged with no sequelae.
新生儿结膜炎通常与分娩过程中阴道被淋病奈瑟菌、沙眼衣原体和/或其他细菌感染有关。脑膜炎球菌性新生儿结膜炎是一种极其罕见的疾病。我们报告了一例新生儿脑膜炎球菌败血症/结膜炎病例，以及父母双方（阴道和鼻咽部）无症状携带淋病奈瑟菌的情况。作为我们在墨西哥蒂华纳总医院（TGH）对脑膜炎球菌病进行主动监测的一部分，我们发现了一名患有脑膜炎球菌性结膜炎和败血症的3日龄新生儿。该患者有一天的结膜炎病史且喂养不佳。临床检查证实结膜有大量脓性分泌物，以及提示菌血症的临床体征和实验室检查结果。结膜渗出物的革兰氏染色显示细胞内革兰氏阴性双球菌；我们推测该婴儿患有淋菌性结膜炎；然而，从结膜渗出物和血液中均分离出了Y群淋病奈瑟菌。此外，从母亲的阴道以及父母双方的鼻咽部分离出了Y群淋病奈瑟菌。该婴儿接受了7天的静脉注射头孢曲松治疗，出院时无后遗症。
