Rouch Joshua D, Dunn James C Y
Department of Surgery, UCLA School of Medicine, Los Angeles, CA 90095.
Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305.
Curr Pediatr Rep. 2017 Mar;5(1):1-5. doi: 10.1007/s40124-017-0119-6. Epub 2017 Feb 2.
This review summarizes recent innovations in the treatment of patients with short bowel syndrome.
The use of surgical procedures, growth factor stimulation, and bioengineering approaches to increase absorptive surface area of the intestine is examined. While the morphology of the intestine is clearly altered by these interventions, it is less clear that the overall function of the intestine is improved.
Continued innovations will likely bring about new therapeutic options for patients with short bowel syndrome. Careful evaluations of the impact of these interventions await controlled clinical trials.
本综述总结了短肠综合征患者治疗方面的近期创新进展。
研究了采用外科手术、生长因子刺激及生物工程方法来增加肠道吸收表面积。虽然这些干预措施明显改变了肠道形态，但肠道整体功能是否得到改善尚不清楚。
持续的创新可能会为短肠综合征患者带来新的治疗选择。对这些干预措施影响的仔细评估有待进行对照临床试验。
