Sjögren E V
Department of ENT and Head and Neck Surgery, Leiden University Medical Center, Albinusdreef 2, 2300 RC Leiden, The Netherlands.
Curr Otorhinolaryngol Rep. 2017;5(1):56-68. doi: 10.1007/s40136-017-0148-2. Epub 2017 Mar 11.
To give an overview of the evolvement of transoral laser microsurgery (TLM) in the treatment of early glottic carcinoma and highlight the contribution of recent literature.
The indications and limits of TLM have been well specified. Effects on swallowing have been well documented. Introduction of narrow-band imaging (NBI) and diffusion-weighted magnetic resonance has been shown of additional value for outcome. The first reports on transoral robotic surgery show that it may be of added value in the future.
TLM for early glottic carcinoma (Tis-T2) has very good oncological outcomes with indications of higher larynx preservation in TLM than that in radiotherapy. The anterior commissure is a risk factor if involved in the cranio-caudal plane, and reduced vocal fold mobility is a risk factor when this is due to arytenoid involvement. The best voice results are achieved when the anterior commissure can be left intact along with part of the vocal fold muscle although even in larger resections, patient self-reported voice handicap is still limited.
概述经口激光显微手术(TLM)在早期声门癌治疗中的发展,并强调近期文献的贡献。
TLM的适应证和局限性已明确界定。对吞咽功能的影响已有充分记录。窄带成像(NBI)和扩散加权磁共振成像的引入已显示出对治疗结果有额外价值。经口机器人手术的首批报告表明,其未来可能具有附加价值。
TLM治疗早期声门癌(Tis-T2)具有非常好的肿瘤学效果,有迹象表明TLM比放射治疗能更好地保留喉功能。如果前联合在头-尾平面受累,则是一个危险因素;当声带运动减少是由于杓状软骨受累时,也是一个危险因素。如果前联合和部分声带肌肉能够保持完整,则可获得最佳的嗓音效果,即使在较大范围的切除术中,患者自我报告的嗓音障碍仍然有限。