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腹主动脉分叉处的计算流体动力学:真实案例研究中的非牛顿血流与牛顿血流

Computational fluid dynamics in abdominal aorta bifurcation: non-Newtonian versus Newtonian blood flow in a real case study.

作者信息

Soares Armando A, Gonzaga Sílvia, Oliveira Carlos, Simões André, Rouboa Abel I

机构信息

a ECT/UTAD - School of Science and Technology , University of Trás-os-Montes e Alto Douro , Vila Real , Portugal.

b CIENER-INEGI - Institute of Science and Innovation in Mechanical and Industrial Engineering , Porto , Portugal.

出版信息

Comput Methods Biomech Biomed Engin. 2017 Jun;20(8):822-831. doi: 10.1080/10255842.2017.1302433. Epub 2017 Apr 3.

Abstract

Hemodynamic in abdominal aorta bifurcation was investigated in a real case using computational fluid dynamics. A Newtonian and non-Newtonian (Walburn-Schneck) viscosity models were compared. The geometrical model was obtained by 3D reconstruction from CT-scan and hemodynamic parameters obtained by laser-Doppler. Blood was assumed incompressible fluid, laminar flow in transient regime and rigid vessel wall. Finite volume-based was used to study the velocity, pressure, wall shear stress (WSS) and viscosity throughout cardiac cycle. Results obtained with Walburn-Schneck's model, during systole, present lower viscosity due to shear thinning behavior. Furthermore, there is a significant difference between the results obtained by the two models for a specific patient. During the systole, differences are more pronounced and are preferably located in the tortuous regions of the artery. Throughout the cardiac cycle, the WSS amplitude between the systole and diastole is greater for the Walburn-Schneck's model than for the Newtonian model. However, the average viscosity along the artery is always greater for the non-Newtonian model, except in the systolic peak. The hemodynamic model is crucial to validate results obtained with CFD and to explore clinical potential.

摘要

利用计算流体动力学对一例真实病例的腹主动脉分叉处血流动力学进行了研究。比较了牛顿和非牛顿(Walburn-Schneck)粘度模型。通过对CT扫描进行三维重建获得几何模型,并通过激光多普勒获得血流动力学参数。假定血液为不可压缩流体,处于瞬态层流且血管壁为刚性。基于有限体积法研究了整个心动周期内的速度、压力、壁面剪应力(WSS)和粘度。Walburn-Schneck模型在收缩期得到的结果显示,由于剪切变稀行为,粘度较低。此外,对于特定患者,两种模型得到的结果存在显著差异。在收缩期,差异更为明显,且更倾向于位于动脉的弯曲区域。在整个心动周期中,Walburn-Schneck模型的收缩期和舒张期之间的WSS幅度比牛顿模型更大。然而,除收缩期峰值外,非牛顿模型沿动脉的平均粘度始终更高。血流动力学模型对于验证CFD获得的结果和探索临床潜力至关重要。

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