van Luin Matthijs, Ter Beest Gerjanne, Wijnberger Lia E, Swanink Caroline Ma, Burger David M, Gisolf Jet H
Department of Clinical Pharmacy, Rijnstate Hospital, Arnhem, the Netherlands.
Department of Internal Medicine, Rijnstate Hospital, Arnhem, the Netherlands.
Antivir Ther. 2017;22(8):727-729. doi: 10.3851/IMP3164.
The authors report the difficulties of preventing mother-to-child transmission in a pregnant HIV-infected woman with a phobia of swallowing pills. After multiple attempts and just as many failures, the authors ended up with cART consisting of small tablets of nevirapine, lamivudine and a continuous intravenous infusion of zidovudine given via an elastomeric pump at home. This case demonstrates the difficulties that HIV physicians can encounter in pregnant women who have difficulties in swallowing tablets. In exceptional circumstances, continuous infusion of zidovudine may be an option, even in an outpatient setting.
作者报告了一名感染艾滋病毒的孕妇因恐惧吞服药物而在预防母婴传播方面遇到的困难。经过多次尝试且同样多次失败后，作者最终采用了由奈韦拉平小片剂、拉米夫定以及通过弹性泵在家持续静脉输注齐多夫定组成的抗逆转录病毒治疗方案。该病例表明，艾滋病毒科医生在遇到吞服片剂困难的孕妇时可能会面临困难。在特殊情况下，即使是在门诊环境中，持续输注齐多夫定也可能是一种选择。
