Żaba Ryszard, Jałowska Magdalena, Kowalczyk Michał J, Bowszyc-Dmochowska Monika, Adamski Zygmunt, Szkaradkiewicz Andrzej
Department of Dermatology and Venerology, Poznań University of Medical Sciences, Poland.
Department of Dermatology, Poznań University of Medical Sciences, Poland.
New Microbiol. 2017 Apr;40(2):148-150. Epub 2017 Apr 3.
Human cowpox represents a seldom diagnosed zoonosis but this diagnosis should be considered more frequently as the number of cases has increased in recent years. We describe a case of cowpox in an 11-yearold boy following regular direct daily contact with a domestic cat. The 11-year-old patient, an otherwise healthy boy, demonstrated skin ulceration located at his chin, with enlargement of regional lymph nodes and fever reaching 39°C. The diagnosis of cowpox was made on the basis of PCR involving DNA isolated from a scab covering the skin lesion. Application of PCR involving DNA isolated from the scab covering the lesion with parallel use of OPXV-specific (ORF F4L) and CPXV-specific (ORF B9R) oligonucleotide primer sequences is recommended for rapid laboratory confirmation of the diagnosis.
人痘苗病是一种很少被诊断出的人畜共患病，但近年来病例数有所增加，因此应更频繁地考虑这一诊断。我们描述了一例11岁男孩的痘苗病病例，该男孩每天与家猫有规律的直接接触。这位11岁的患者是一名其他方面健康的男孩，下巴处出现皮肤溃疡，局部淋巴结肿大，体温高达39°C。痘苗病的诊断是基于从覆盖皮肤病变的痂皮中分离出的DNA进行PCR检测得出的。建议应用从覆盖病变的痂皮中分离出的DNA进行PCR检测，并同时使用痘苗病毒特异性（ORF F4L）和牛痘病毒特异性（ORF B9R）寡核苷酸引物序列，以便在实验室快速确诊。
