Academic Unit of Radiology, University of Sheffield, Sheffield, UK.
Academic Radiology, University of Sheffield, Sheffield, South Yorkshire, UK.
Prenat Diagn. 2017 Jun;37(6):556-565. doi: 10.1002/pd.5042. Epub 2017 May 15.
In our earlier publication, we described the methods of acquiring 3D volume MR data in second and third trimester fetuses and provided normative data from a large cohort of normal fetuses. In this article, we show the applicability of the technique by describing five fetuses with a range of developmental brain abnormalities.
The five cases described in this report all had an intra-cranial abnormality recognised on prenatal ultrasonography, which precipitated referral for in utero MR imaging. This consisted of routine ultrafast 2D sequences and 3D volume imaging acquired using balanced steady-state imaging (Fast Imaging Employing Steady-state Imaging - FIESTA). The 3D data were used to reconstruct models of the fetal brains and hence derive representations of the surfaces of the brain and estimates of volumes of the intracranial compartments.
These cases show several important features of relevance for diagnosing intracranial fetal pathology.
3D volume in utero MR imaging appears to be a promising method in the prenatal assessment of the fetal brain. We propose possible areas of future research that are required to assess the techniques potential to have clinical impact. © 2017 John Wiley & Sons, Ltd.
在我们之前的出版物中，我们描述了在第二和第三个孕期胎儿中获取 3D 容积 MR 数据的方法，并提供了大量正常胎儿的规范数据。在本文中，我们通过描述五例具有一系列发育性脑异常的胎儿来展示该技术的适用性。
本报告中描述的五个病例均在产前超声检查中发现颅内异常，这促使他们转介进行宫内磁共振成像检查。该检查包括使用平衡稳态成像（Fast Imaging Employing Steady-state Imaging - FIESTA）获取常规超快 2D 序列和 3D 容积成像。3D 数据用于重建胎儿大脑模型，从而得出大脑表面的表示和颅内腔室容积的估计。
这些病例显示了一些与颅内胎儿病理学诊断相关的重要特征。
3D 容积宫内磁共振成像似乎是产前评估胎儿大脑的一种很有前途的方法。我们提出了未来需要研究的可能领域，以评估该技术在临床应用方面的潜力。© 2017 约翰威立父子公司。
