与慢性移植物抗宿主病相关的获得性部分脂肪营养不良中胰岛素需求的暂时缓解。

Temporary resolution of insulin requirement in acquired partial lipodystrophy associated with chronic graft-versus-host disease.

作者信息

Kimura Leslie, Alvarez Griselda, Li Ning, Pawlikowska-Haddal Anna, Moore Theodore B, Casillas Jacqueline, Lee Kuk-Wha

机构信息

Department of Pediatric Endocrinology, UCLA Mattel Children's Hospital, Los Angeles, California.

Department of Pediatric Endocrinology, Children's Hospital of Los Angeles, Los Angeles, California.

出版信息

Pediatr Blood Cancer. 2017 Jul;64(7). doi: 10.1002/pbc.26427. Epub 2017 Mar 29.

DOI:10.1002/pbc.26427

PMID:28371314

Abstract

This is a case presentation describing a high insulin requirement that suddenly resolved in a patient with acute lymphoblastic leukemia treated with stem cell transplantation complicated by chronic graft-versus-host disease. The patient was diagnosed with acquired partial lipodystrophy that did not require alternative therapies such as leptin or insulin-like growth factor 1.

摘要

这是一个病例报告，描述了一名接受干细胞移植治疗并发慢性移植物抗宿主病的急性淋巴细胞白血病患者，其高胰岛素需求突然消失。该患者被诊断为获得性部分脂肪营养不良，无需使用瘦素或胰岛素样生长因子1等替代疗法。