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一只患有脑侵袭的犬原发性鼻内黑色素瘤。

Primary intranasal melanoma with brain invasion in a dog.

作者信息

Lemetayer Julie, Al-Dissi Ahmad, Tryon Kim, MacDonald-Dickinson Valerie

机构信息

Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1 (Lemetayer); Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4 (Al-Dissi, Tryon, MacDonald-Dickinson).

出版信息

Can Vet J. 2017 Apr;58(4):391-396.

PMID:28373733
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5347331/
Abstract

A 6-year-old castrated male boxer dog with right-sided dark purulent nasal discharge and acute bilateral blindness was diagnosed on magnetic resonance imaging (MRI) and then on necropsy with primary nasal malignant melanoma that extended into the brain, as well as concurrent ocular melanosis. There was no evidence of metastasis in other organs.

摘要

一只6岁去势雄性拳师犬,右侧鼻腔有脓性黑色分泌物且双眼急性失明,经磁共振成像(MRI)诊断,尸检发现为原发性鼻腔恶性黑色素瘤,肿瘤已蔓延至脑部,同时伴有眼黑变病。其他器官无转移迹象。

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Primary intranasal melanoma with brain invasion in a dog.一只患有脑侵袭的犬原发性鼻内黑色素瘤。
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本文引用的文献

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Outcome following curative-intent surgery for oral melanoma in dogs: 70 cases (1998-2011).犬口腔黑色素瘤根治性手术的治疗结果:70例病例(1998 - 2011年)
J Am Vet Med Assoc. 2014 Dec 1;245(11):1266-73. doi: 10.2460/javma.245.11.1266.
2
Efficacy and side effects of radiation therapy in comparison with radiation therapy and temozolomide in the treatment of measurable canine malignant melanoma.比较放疗与放疗联合替莫唑胺治疗可测量犬恶性黑色素瘤的疗效和副作用。
Vet Comp Oncol. 2016 Dec;14(4):e146-e157. doi: 10.1111/vco.12122. Epub 2014 Nov 10.
3
Sinonasal malignancy: presentation and outcomes.鼻窦恶性肿瘤:临床表现与治疗结果
J Laryngol Otol. 2014 Jul;128(7):654-7. doi: 10.1017/S0022215114001066.
4
Efficacy of systemic adjuvant therapies administered to dogs after excision of oral malignant melanomas: 151 cases (2001-2012).对口腔恶性黑色素瘤切除术后的犬进行全身辅助治疗的疗效:151例病例(2001 - 2012年)
J Am Vet Med Assoc. 2014 Aug 15;245(4):401-7. doi: 10.2460/javma.245.4.401.
5
Mucosal melanoma of the nasal cavity and paranasal sinuses.鼻腔和鼻窦黏膜黑色素瘤。
Eur Ann Otorhinolaryngol Head Neck Dis. 2014 Dec;131(6):365-369. doi: 10.1016/j.anorl.2013.11.004. Epub 2014 Jun 3.
6
CSPG4-specific immunity and survival prolongation in dogs with oral malignant melanoma immunized with human CSPG4 DNA.用人CSPG4 DNA免疫的口腔恶性黑色素瘤犬的CSPG4特异性免疫和生存期延长
Clin Cancer Res. 2014 Jul 15;20(14):3753-62. doi: 10.1158/1078-0432.CCR-13-3042. Epub 2014 May 29.
7
A retrospective analysis of the efficacy of Oncept vaccine for the adjunct treatment of canine oral malignant melanoma.回顾性分析 Oncept 疫苗辅助治疗犬口腔恶性黑色素瘤的疗效。
Vet Comp Oncol. 2013 Sep;11(3):219-29. doi: 10.1111/vco.12057.
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Malignant melanoma in 63 dogs (2001-2011): the effect of carboplatin chemotherapy on survival.63只犬的恶性黑色素瘤(2001 - 2011年):卡铂化疗对生存的影响
N Z Vet J. 2013 Jan;61(1):25-31. doi: 10.1080/00480169.2012.699433. Epub 2012 Aug 23.
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Use of adjuvant carboplatin for treatment of dogs with oral malignant melanoma following surgical excision.辅助性卡铂用于手术切除后口腔恶性黑色素瘤犬的治疗。
Vet Comp Oncol. 2014 Mar;12(1):78-84. doi: 10.1111/j.1476-5829.2012.00338.x. Epub 2012 Jun 28.
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Am J Vet Res. 2011 Dec;72(12):1631-8. doi: 10.2460/ajvr.72.12.1631.