Melosky Barbara
Medical Oncology, British Columbia Cancer Agency, Vancouver Centre , Vancouver, BC , Canada.
Front Oncol. 2017 Mar 20;7:38. doi: 10.3389/fonc.2017.00038. eCollection 2017.
The treatment paradigm for metastatic non-small cell, non-squamous lung cancer is continuously evolving due to new treatment options and our increasing knowledge of molecular signal pathways. As a result of treatments becoming more efficacious and more personalized, survival for selected groups of non-small cell lung cancer (NSCLC) patients is increasing. In this paper, three algorithms will be presented for treating patients with metastatic non-squamous, NSCLC. These include treatment algorithms for NSCLC patients whose tumors have mutations, rearrangements, or wild-type/wild-type tumors. As the world of immunotherapy continues to evolve quickly, a future algorithm will also be presented.
由于新的治疗选择以及我们对分子信号通路的认识不断增加,转移性非小细胞非鳞状肺癌的治疗模式正在不断演变。随着治疗变得更加有效和个性化,部分非小细胞肺癌(NSCLC)患者的生存期正在延长。本文将介绍三种用于治疗转移性非鳞状NSCLC患者的算法。这些算法包括针对肿瘤有特定突变、重排或野生型/野生型肿瘤的NSCLC患者的治疗算法。随着免疫治疗领域的快速发展,还将介绍一种未来的算法。