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认知状态、快速行走速度和行走速度储备——步态与阿尔茨海默病相互作用追踪研究(GAIT 研究)。

Cognitive status, fast walking speed and walking speed reserve-the Gait and Alzheimer Interactions Tracking (GAIT) study.

机构信息

Menzies Institute for Medical Research, University of Tasmania, 17 Liverpool Street, Hobart, Tasmania, Australia.

Stroke and Ageing Research Group, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Australia.

出版信息

Geroscience. 2017 Apr;39(2):231-239. doi: 10.1007/s11357-017-9973-y. Epub 2017 Apr 3.

Abstract

The aims of this study were to (1) determine if older people at their fast walking speed (FWS) are able to reach the speed required at pedestrian crossings (>1.2 m/s) and (2) determine the role of cognitive impairment on the ability to alter speed and walk quickly. Participants were recruited from the Angers Memory Clinic, France. Gait speed was assessed at preferred and FWS using a GAITRite walkway. Walking speed reserve (WSR) was calculated as the difference between FWS and preferred speeds. Participants were classified into cognitive stages (cognitively healthy, mild cognitive impairment, mild and moderate dementia) based on neuropsychological evaluations. The proportion of participants with a FWS of <1.2 m/s was reported. The association between cognitive stage and preferred, fast and walking speed reserve was assessed using multivariable regression, adjusting for covariates. The mean age of the sample (n = 681) was 73.3 (SD 5.8) years. At preferred speed 73.7%, and at FWS 12.8%, of participants had speeds less than 1.2 m/s. Poorer cognitive stage was associated with slower preferred speed (β -0.08, 95% CI -0.10, -0.06), FWS (β -0.13, 95% CI -0.16, -0.10) and also with smaller WSR (m/s) (β -0.05, 95% CI -0.07, -0.03), but not WSR (%) (β -1.73, 95% CI -4.38, 0.93). In older people, worse stages of cognitive impairment were associated with poorer ability to increase speed and walk quickly. Such limitations may result in reduced ability to access the community.

摘要

本研究旨在

(1) 确定老年人在快速步行速度(FWS)下是否能够达到行人穿越速度(>1.2m/s)的要求;(2) 确定认知障碍对改变速度和快速行走能力的影响。参与者是从法国昂热记忆诊所招募的。使用 GAITRite 步道评估了他们的步速,包括在舒适和 FWS 速度下的步速。步行速度储备(WSR)定义为 FWS 与舒适速度之间的差值。根据神经心理学评估,参与者被分为认知阶段(认知健康、轻度认知障碍、轻度和中度痴呆)。报告了 FWS<1.2m/s 的参与者比例。使用多变量回归,调整协变量后,评估认知阶段与舒适、快速和步行速度储备之间的关系。样本的平均年龄(n=681)为 73.3(SD 5.8)岁。在舒适速度下,73.7%的参与者,在 FWS 下,12.8%的参与者的速度小于 1.2m/s。认知阶段越差,与舒适速度(β-0.08,95%CI-0.10,-0.06)、FWS(β-0.13,95%CI-0.16,-0.10)以及更小的 WSR(m/s)(β-0.05,95%CI-0.07,-0.03)相关,但与 WSR(%)(β-1.73,95%CI-4.38,0.93)无关。在老年人中,认知障碍的严重程度越差,提高速度和快速行走的能力越差。这种限制可能会导致他们难以进入社区。

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