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Optogenetic activation of dorsal raphe neurons rescues the autistic-like social deficits in Shank3 knockout mice.

作者信息

Luo Junyu, Feng Qiru, Wei Liping, Luo Minmin

机构信息

Peking University-Tsinghua University-National Institute of Biological Sciences (PTN) Joint Graduate Program, School of Life Sciences, Tsinghua University, Beijing 100084, China.

School of Life Sciences, Peking University, Beijing 100871, China.

出版信息

Cell Res. 2017 Jul;27(7):950-953. doi: 10.1038/cr.2017.52. Epub 2017 Apr 4.

DOI:10.1038/cr.2017.52
PMID:28374752
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5518984/
Abstract
摘要

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本文引用的文献

1
SHANK3 controls maturation of social reward circuits in the VTA.SHANK3控制腹侧被盖区社交奖励回路的成熟。
Nat Neurosci. 2016 Jul;19(7):926-934. doi: 10.1038/nn.4319. Epub 2016 Jun 6.
2
Dopamine Prediction Errors in Reward Learning and Addiction: From Theory to Neural Circuitry.奖励学习与成瘾中的多巴胺预测误差:从理论到神经回路
Neuron. 2015 Oct 21;88(2):247-63. doi: 10.1016/j.neuron.2015.08.037.
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Natural neural projection dynamics underlying social behavior.社会行为背后的自然神经投射动力学。
Cell. 2014 Jun 19;157(7):1535-51. doi: 10.1016/j.cell.2014.05.017.
4
Dorsal raphe neurons signal reward through 5-HT and glutamate.中缝背核神经元通过 5-HT 和谷氨酸传递奖励信号。
Neuron. 2014 Mar 19;81(6):1360-1374. doi: 10.1016/j.neuron.2014.02.010.
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Autism spectrum disorder causes, mechanisms, and treatments: focus on neuronal synapses.自闭症谱系障碍的病因、机制和治疗方法:聚焦于神经元突触。
Front Mol Neurosci. 2013 Aug 5;6:19. doi: 10.3389/fnmol.2013.00019. eCollection 2013.
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Reward system dysfunction in autism spectrum disorders.自闭症谱系障碍中的奖励系统功能障碍。
Soc Cogn Affect Neurosci. 2013 Jun;8(5):565-72. doi: 10.1093/scan/nss033. Epub 2012 Mar 13.
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Shank3 mutant mice display autistic-like behaviours and striatal dysfunction.Shank3 突变小鼠表现出自闭症样行为和纹状体功能障碍。
Nature. 2011 Apr 28;472(7344):437-42. doi: 10.1038/nature09965. Epub 2011 Mar 20.
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Applied behavior analytic interventions for children with autism: a description and review of treatment research.针对自闭症儿童的应用行为分析干预:治疗研究的描述与综述
Ann Clin Psychiatry. 2009 Jul-Sep;21(3):162-73.
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Early behavioral intervention, brain plasticity, and the prevention of autism spectrum disorder.早期行为干预、大脑可塑性与自闭症谱系障碍的预防
Dev Psychopathol. 2008 Summer;20(3):775-803. doi: 10.1017/S0954579408000370.
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Characterization of a mouse strain expressing Cre recombinase from the 3' untranslated region of the dopamine transporter locus.一种从多巴胺转运体基因座的3'非翻译区表达Cre重组酶的小鼠品系的特性分析。
Genesis. 2006 Aug;44(8):383-90. doi: 10.1002/dvg.20228.