Ramachandran A, Neelan P N
Central Leprosy Teaching & Research Institute, Chengalpattu, Tamil Nadu.
Indian J Lepr. 1987 Oct-Dec;59(4):405-13.
21 patients of borderline lepromatous and lepromatous leprosy of both sexes were taken for study after exclusion of autonomic disorders. Autonomic functions pertaining to cardiovascular and genital system were carried out. Five healthy volunteers served as controls. Autonomic function tests indicate definite involvement of cardiovascular and genital system. The incidence of autonomic neuropathy in 21 patients studied was ranging from 14.3 to 57% for various tests. There is involvement of parasympathetic system (vagus nerve) which occurred early and more common than sympathetic. The sympathetic damage is always associated with parasympathetic damage. The severity of autonomic neuropathy is found to be high in leprosy of longer duration. Autonomic neuropathy widely occurs in leprosy as in diabetes mellitus.
在排除自主神经功能障碍后，选取了21例男女界限类偏瘤型和瘤型麻风患者进行研究。对心血管和生殖系统的自主神经功能进行了检测。5名健康志愿者作为对照。自主神经功能测试表明心血管和生殖系统确实受到了影响。在接受研究的21例患者中，各种测试的自主神经病变发生率在14.3%至57%之间。副交感神经系统（迷走神经）受累，且出现较早，比交感神经更常见。交感神经损伤总是与副交感神经损伤相关。发现病程较长的麻风患者自主神经病变的严重程度较高。自主神经病变在麻风病中广泛存在，如同在糖尿病中一样。
