Shah P K, Malhotra Y K, Lakhotia M, Kothari A, Jain S K, Mehta S
Dr. S.N. Medical College Hospital, Jodhpur.
Indian J Lepr. 1990 Jan-Mar;62(1):91-7.
Autonomic functions were studied by six standard tests in 65 patients with lepromatous leprosy and 25 healthy controls. Dysautonomia was observed in 22 patients, all having the disease for more than five years. Associated peripheral neuropathy, judged clinically, was present in all, except one patient. Of the 22 dysautonomic patients, 9 each had mild or moderate dysantonomia and 4 had severe dysautonomia as per the scoring schedule devised by us. Syncope, gustatory sweating and impotence were the symptoms suggestive of dysautonomia. But not all affected patients reported these symptoms. Involvement of the sympathetic system was more frequent than that of the parasympathetic system. Statistically significant abnormality was seen with Atropine ratio, standing 30:15 beat ratio, postural hypotension and sustained hand grip test. Sustained hand grip test was the one which consistently gave abnormal results in all the 22 dysautonomic patients.
通过六项标准测试，对65例瘤型麻风患者和25名健康对照者的自主神经功能进行了研究。在22例患者中观察到自主神经功能障碍，所有患者病程均超过五年。除一名患者外，所有患者经临床判断均伴有周围神经病变。根据我们制定的评分标准，在这22例自主神经功能障碍患者中，9例有轻度或中度自主神经功能障碍，4例有重度自主神经功能障碍。晕厥、味觉性出汗和阳痿是提示自主神经功能障碍的症状。但并非所有受影响的患者都报告了这些症状。交感神经系统受累比副交感神经系统更常见。阿托品比率、站立30:15心跳比率、体位性低血压和持续握力测试有统计学意义的异常。持续握力测试在所有22例自主神经功能障碍患者中均持续给出异常结果。
