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IgG4相关性主动脉炎:一例报告

IgG4 Aortitis: A Case Report.

作者信息

Marketkar Shivali, LeGolvan Mark

机构信息

Resident in Pathology, Rhode Island Hospital/ Alpert Medical School of Brown University, Providence, RI.

Pathologist, Rhode Island Hospital, Assistant Professor of Pathology and Laboratory Medicine (Clinical), Alpert Medical School of Brown University, Providence, RI.

出版信息

R I Med J (2013). 2017 Apr 3;100(4):29-32.

Abstract

IgG4 aortitis is one of the entities seen in the spectrum of IgG4-related disease (IgG4-RD). It is characterized by serologic (elevated serum IgG4) and histologic features including a lymphoplasmacytic infiltrate with increased numbers of IgG4-positive plasma cells, storiform fibrosis and obliterative phlebitis. Some studies have described a correlation between infections and IgG4 aortitis. We describe a patient with an aneurysm of the infrarenal descending abdominal aorta with features of IgG4-RD, as well as culture evidence of Streptococcus sanguis. [Full article available at http://rimed.org/rimedicaljournal-2017-04.asp].

摘要

IgG4 相关性主动脉炎是 IgG4 相关疾病(IgG4-RD)谱系中的一种疾病。其特征包括血清学表现(血清 IgG4 升高)以及组织学特征,如淋巴细胞和浆细胞浸润伴 IgG4 阳性浆细胞数量增加、席纹状纤维化和闭塞性静脉炎。一些研究描述了感染与 IgG4 相关性主动脉炎之间的关联。我们报告一例患有肾下腹主动脉降段动脉瘤且具有 IgG4-RD 特征的患者,同时有血链球菌感染的培养证据。[全文可在 http://rimed.org/rimedicaljournal-2017-04.asp 获取]

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