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食管裂孔疝复发和食管裂孔修复失败的时间模式:翻修手术后的生活质量和复发情况

Temporal patterns of hiatus hernia recurrence and hiatal failure: quality of life and recurrence after revision surgery.

作者信息

Suppiah A, Sirimanna P, Vivian S J, O'Donnell H, Lee G, Falk G L

机构信息

Concord Repatriation General Hospital, Sydney, Australia.

The University of Sydney, NSW2006, Australia.

出版信息

Dis Esophagus. 2017 Apr 1;30(4):1-8. doi: 10.1093/dote/dow035.

DOI:10.1093/dote/dow035
PMID:28375479
Abstract

Antireflux and paraesophageal hernia repair surgery is increasingly performed and there is an increased requirement for revision hiatus hernia surgery. There are no reports on the changes in types of failures and/or the variations in location of crural defects over time following primary surgery and limited reports on the outcomes of revision surgery. The aim of this study is to report the changes in types of hernia recurrence and location of crural defects following primary surgery, to test our hypothesis of the temporal events leading to hiatal recurrence and aid prevention. Quality of life scores following revision surgery are also reported, in one of the largest and longest follow-up series in revision hiatus surgery. Review of a single-surgeon database of all revision hiatal surgery between 1992 and 2015. The type of recurrence and the location of crural defect were noted intraoperatively. Recurrence was diagnosed on gastroscopy and/or contrast study. Quality of life outcomes were measured using Visick, dysphagia, atypical reflux symptoms, satisfaction scores, and Gastrointestinal Quality of Life Index (GIQLI). Two-hundred eighty four patients (126 male, 158 female), median age 60.8(48.2-69.1), underwent revision hiatal surgery. Median follow-up following primary surgery was 122.8(75.3-180.3) and 91.6(40.5-152.5) months after revision surgery. The most common type of hernia recurrence in the early period after primary surgery was 'telescope'(42.9%), but overall, fundoplication apparatus transhiatal migration was consistently the predominant type of recurrence at 1-3 years (54.3%), 3-5 years (42.5%), 5-10 years (45.1%), and >10 years (44.1%). The location of crural defects changed over duration following primary surgery as anteroposterior defects was most common in the early period (45.5% in <1 year) but decreased over time (30.3% at 1-3 years) while anterior defects increased in the long term with 35.9%, 40%, and 42.2% at 3-5 years, 5-10 years, and >10 years, respectively. Revision surgery intraoperative morbidity was 19.7%, mainly gastric (9.5%) and esophageal (2.1%) perforation. There was a 75% follow-up rate and recurrence following revision surgery was 15.4%(44/284) in unscreened population and 21%(44/212) in screened population. There was no difference in recurrence rate based on size of hiatus hernia at primary surgery, or at revision surgery. There were significant improvements in the Visick score (3.3 vs. 2.4), the modified Dakkak score (23.2 vs. 15.4), the atypical reflux symptom score (23.7 vs. 15.4), and satisfaction scores (0.9 vs. 2.2), but no difference in the various domains (symptom, physical, social, and medical) of the GIQLI scores following revision surgery. Revision hiatal surgery has higher intraoperative morbidity but may achieve adequate long-term satisfaction and quality of life. The most common type of early recurrence following primary surgery is telescoping, and overall is wrap herniation. Anterior crural defects may be strong contributor to late hiatus hernia recurrence. Symptom-specific components of GIQLI, but not the overall GIQLI score, may be required to detect improvements in QOL.

摘要

抗反流和食管旁疝修补手术的开展越来越多,对复发性食管裂孔疝手术的需求也在增加。目前尚无关于初次手术后失败类型的变化和/或膈肌脚缺损位置随时间变化的报道,关于复发性手术结果的报道也很有限。本研究的目的是报告初次手术后疝复发类型和膈肌脚缺损位置的变化,验证我们关于导致食管裂孔疝复发的时间事件的假设,并有助于预防。本文还报告了复发性手术后的生活质量评分,这是复发性食管裂孔疝手术中规模最大、随访时间最长的系列研究之一。回顾了1992年至2015年间一位外科医生进行的所有复发性食管裂孔疝手术的数据库。术中记录复发类型和膈肌脚缺损位置。通过胃镜检查和/或造影检查诊断复发情况。使用Visick评分、吞咽困难评分、非典型反流症状评分、满意度评分和胃肠道生活质量指数(GIQLI)来衡量生活质量结果。284例患者(男126例,女158例)接受了复发性食管裂孔疝手术,中位年龄60.8岁(48.2 - 69.1岁)。初次手术后的中位随访时间为122.8个月(75.3 - 180.3个月),复发性手术后为91.6个月(40.5 - 152.5个月)。初次手术后早期最常见的疝复发类型是“套叠”(42.9%),但总体而言,胃底折叠装置经食管裂孔移位一直是1 - 3年(54.3%)、3 - 5年(42.5%)、5 - 10年(45.1%)和>10年(44.1%)时复发的主要类型。初次手术后膈肌脚缺损的位置随时间而变化,前后位缺损在早期最常见(<1年时为45.5%),但随时间减少(1 - 3年时为30.3%),而前位缺损长期增加,在3 - 5年、5 - 10年和>10年时分别为35.9%、40%和42.2%。复发性手术的术中发病率为19.7%,主要是胃穿孔(9.5%)和食管穿孔(2.1%)。随访率为75%,复发性手术后未筛查人群的复发率为15.4%(44/284),筛查人群为21%(44/212)。初次手术或复发性手术时食管裂孔疝的大小与复发率无差异。Visick评分(3.3对2.4)、改良Dakkak评分(23.2对15.4)、非典型反流症状评分(23.7对15.4)和满意度评分(0.9对2.2)有显著改善,但复发性手术后GIQLI评分的各个领域(症状、身体、社会和医疗)无差异。复发性食管裂孔疝手术的术中发病率较高,但可能实现足够的长期满意度和生活质量。初次手术后早期最常见的复发类型是套叠,总体是胃底折叠装置疝出。前位膈肌脚缺损可能是晚期食管裂孔疝复发的重要原因。可能需要GIQLI的症状特异性成分,而不是总体GIQLI评分,来检测生活质量的改善情况。

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