Komaki K, Sakamoto G, Sugano H, Kasumi F, Nishi M
Dept. of Pathology, Cancer Institute.
Gan No Rinsho. 1988 May;34(6):765-72.
Cases of early invasive mucinous carcinoma of the breast have been reviewed. Microscopically, a typical lesion exhibits leakage of cancerous mucus into the stromal tissue from an intraductal carcinomatous component which were shown to be mucus-producing and to be lower papillary projection. Among 5,360 primary breast cancers that had been mastectomized at the C.I.H., 11 or 0.21% were determined as being "early" cases. All of these cases exhibited "pure type" mucinous carcinomas which were found to be highly mucus. The average age of these patients was 41 years (range: 34-51 yrs.), and no cases showed a nodal involvement. During an average follow-up of 8 years, no recurrent case were found. Thus, we have found that these "early" cases revealed an early invasion of a mucinous carcinoma that is highly mucus-producing but without an invasive ductal carcinomatous pattern.
对早期浸润性乳腺黏液癌病例进行了回顾。显微镜下，典型病变表现为癌性黏液从导管内癌成分漏入间质组织，导管内癌成分显示为产生黏液且呈低乳头状突起。在CIH接受乳房切除术的5360例原发性乳腺癌中，11例（0.21%）被确定为“早期”病例。所有这些病例均表现为“纯型”黏液癌，发现其黏液含量很高。这些患者的平均年龄为41岁（范围：34 - 51岁），且无一例出现淋巴结受累。在平均8年的随访期间，未发现复发病例。因此，我们发现这些“早期”病例显示出一种高度产生黏液但无浸润性导管癌模式的黏液癌早期浸润。
