Vagal Afferent Research Group, Centre for Nutrition and Gastrointestinal Diseases, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia.
South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia.
Acta Physiol (Oxf). 2018 Jan;222(1). doi: 10.1111/apha.12884. Epub 2017 May 3.
Neuropeptide W is the endogenous ligand for G-protein-coupled receptors GPR7 and GPR8. In this review, we summarize findings on the distribution of neuropeptide W and its receptors in the central nervous system and the periphery, and discuss the role of NPW in food intake and energy homeostasis.
神经肽 W 是 G 蛋白偶联受体 GPR7 和 GPR8 的内源性配体。在这篇综述中,我们总结了神经肽 W 及其受体在中枢神经系统和外周的分布,并讨论了 NPW 在摄食和能量平衡中的作用。