Comandone A, Sciascia C, Enrichens F, Olivero G, Foco A, Fiori M G, Sanfelici G, Gallingani R
Istituto di Chirurgia d'Urgenza, Università di Torino.
Minerva Med. 1988 Jun;79(6):455-61.
The importance of sexual hormones in the development of cancers of the large bowel is strongly supported experimentally and epidemiologically. The clinical search for the presence of hormonal receptors in the cells of patients operated for tumours of the colon and rectum has been common since 1975. This investigation ought to have opened up new diagnostic and therapeutic prospects for these tumours which have given such a little curative satisfaction. The present review considered reported data. Unfortunately the emerging picture is irregular in cases and results. It is personally considered that these studies are not for the moment likely to produce important novelties for the treatment of tumours of the large bowel tract.
性激素在大肠癌发生发展中的重要性在实验和流行病学方面都得到了有力支持。自1975年以来，临床上一直在探寻接受结肠和直肠肿瘤手术患者的细胞中是否存在激素受体。这项研究本应为这些疗效不尽人意的肿瘤开辟新的诊断和治疗前景。本综述考量了已报道的数据。遗憾的是，病例和结果呈现出的情况并不规律。个人认为，目前这些研究不太可能为大肠肿瘤的治疗带来重大新进展。
