Bershteĭn L M, Bobrov Iu F, Ostroumova M N, Kovaleva I G, Kovalenko I G
Eksp Onkol. 1988;10(3):38-41.
Peculiarities of hormone-metabolic status in patients with cancer of the rectum and colon consist of 1) symptoms of cancrophilia, 2) disturbances of enteric endocrine system and 3) properties of the tumour tissue, determining first of all its hormone sensitivity. Determination of steroid hormone (estrogens and progesterone) receptors does not appear a sufficiently informative criterion of colorectal cancer tissue hormone sensitivity; the adenylate cyclase reaction to the hormonal stimulators is more informative in this respect. The data obtained may be useful in the working out of adjuvant therapy methods in cancer of colon and rectum (including hormonotherapy and metabolic rehabilitation).
1）癌嗜性症状；2）肠道内分泌系统紊乱；3）肿瘤组织的特性，这首先决定了其激素敏感性。甾体激素（雌激素和孕激素）受体的测定似乎并非评估结直肠癌组织激素敏感性的充分信息标准；在这方面，激素刺激物对腺苷酸环化酶的反应提供了更多信息。所获得的数据可能有助于制定结肠癌和直肠癌的辅助治疗方法（包括激素疗法和代谢康复）。
