Dedeoglu Reyhan, Barut Kenan, Oztunc Funda, Atik Sezen, Adrovic Amra, Sahin Sezgin, Cengiz Dicle, Kasapcopur Ozgur
Pediatric Cardiology,Dr. Siyami Ersek Chest, Heart and Vessel Surgery Teaching and Research Hospital,Siyami Ersek Hospital,Istanbul,Turkey.
Cardiol Young. 2017 Sep;27(7):1377-1385. doi: 10.1017/S1047951117000580. Epub 2017 Apr 5.
Speckle-tracking echocardiography is a recently developed technique for the evaluation of myocardial deformation or strain. Our objective was to examine strain through a mid-term follow-up of patients with Kawasaki disease.
We explored left ventricular mechanics using speckle-tracking echocardiography in 35 patients with a history of Kawasaki disease at least 6 months after the acute phase. We also included 30 healthy children as controls. Strain data sets were acquired for the quantification of left ventricular global strain, segmental strain, and left ventricular ejection fraction.
The mean age of our patients was 25.6±15.4 months. At a median follow-up of 57.5 months (16.5-98.2), although both values were in the normal range, the mean left ventricular ejection proportion of patients (57.3%) was a little lower than that of controls (p⩽0.05). Patient strain values at the basal inferoseptal (20.0), basal anterolateral (19.5), apical septal (23.3), and apical inferior (24.0) segments were lower compared with controls. In all, seven patients had coronary aneurysms during follow-up. Kawasaki disease patients with pyuria had lower left ventricular strain at the mid anterior, mid anteroseptal, apical anterior, and apical inferior segments and global longitudinal strain compared with patients with no pyuria (p⩽0.05).
In children with a history of Kawasaki disease, impairment of left ventricular mechanics occurs especially within the left anterior descending artery territories.
斑点追踪超声心动图是一种最近开发的用于评估心肌变形或应变的技术。我们的目的是通过对川崎病患者的中期随访来检查应变情况。
我们使用斑点追踪超声心动图对35例急性期后至少6个月有川崎病病史的患者的左心室力学进行了研究。我们还纳入了30名健康儿童作为对照。获取应变数据集以量化左心室整体应变、节段应变和左心室射血分数。
我们患者的平均年龄为25.6±15.4个月。在中位随访57.5个月（16.5 - 98.2）时，尽管两个值均在正常范围内，但患者的平均左心室射血比例（57.3%）略低于对照组（p⩽0.05）。与对照组相比，患者在基底下间隔（20.0）、基底前外侧（19.5）、心尖间隔（23.3）和心尖下（24.0）节段的应变值较低。在随访期间，共有7例患者出现冠状动脉瘤。与无脓尿的川崎病患者相比，有脓尿的川崎病患者在左心室中前、中前间隔、心尖前和心尖下节段以及整体纵向应变方面较低（p⩽0.05）。
在有川崎病病史的儿童中，左心室力学受损尤其发生在左前降支动脉区域内。
