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解析强迫性抽动障碍(OCTD)的表型:多学科共识

Parsing the phenotype of obsessive-compulsive tic disorder (OCTD): a multidisciplinary consensus.

作者信息

Dell'Osso Bernardo, Marazziti Donatella, Albert Umberto, Pallanti Stefano, Gambini Orsola, Tundo Antonio, Zanaboni Carlotta, Servello Domenico, Rizzo Renata, Scalone Luciana, Benatti Beatrice, Altamura A Carlo, Porta Mauro

机构信息

a Department of Psychiatry, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico , University of Milan , Milan , Italy.

b Department of Psychiatry and Behavioral Sciences , Stanford University , CA , USA.

出版信息

Int J Psychiatry Clin Pract. 2017 Jun;21(2):156-159. doi: 10.1080/13651501.2017.1291822. Epub 2017 Feb 24.

Abstract

Obsessive-Compulsive Disorder (OCD) and Tic Disorder (TD) are highly disabling and often comorbid conditions. Of note, the DSM-5 acknowledged a new 'tic-related' specifier for OCD, which might be referred to as Obsessive-Compulsive Tic Disorder (OCTD), raising new interest toward a better clinical characterisation of affected patients. Available literature indicates that early onset, male gender, sensory phenomena and obsessions of symmetry, aggressiveness, hoarding, exactness and sounds as well as comorbidity with Attention Deficit Hyperactivity Disorder (ADHD) may be of more frequent observation in patients with OCTD. In order to share expertise in the field from different perspectives, a multidisciplinary panel of Italian clinicians, specifically involved in the clinical care of OCD and TD patients, participated into a consensus initiative, aimed to produce a shared document. As a result, after having examined the most relevant literature, authors sought to critically identify and discuss main epidemiologic, socio-demographic and clinical features characterising OCTD patients, along with other specific aspects including Health-Related Quality-of-Life (HRQoL), economic consequences related with the condition and its management, as well as treatment-related issues, that need to be further investigated.

摘要

强迫症(OCD)和抽动障碍(TD)是严重致残且常合并出现的病症。值得注意的是,《精神疾病诊断与统计手册》第五版(DSM - 5)认可了一种新的强迫症“抽动相关”说明符,这可能被称为强迫性抽动障碍(OCTD),引发了人们对更好地临床描述受影响患者的新兴趣。现有文献表明,早发、男性、感觉现象以及对称、攻击性、囤积、精确性和声音方面的强迫观念,以及与注意力缺陷多动障碍(ADHD)的共病情况,在OCTD患者中可能更常被观察到。为了从不同角度分享该领域的专业知识,一个专门参与强迫症和抽动障碍患者临床护理的意大利临床医生多学科小组参与了一项共识倡议,旨在生成一份共享文件。结果是在查阅了最相关的文献后,作者们试图批判性地识别和讨论表征OCTD患者的主要流行病学、社会人口统计学和临床特征,以及其他特定方面,包括健康相关生活质量(HRQoL)、与病情及其管理相关的经济后果,以及需要进一步研究的治疗相关问题。

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