Kito T, Yamamura Y
Dept. of Gastroenterological Surgery, Aichi Cancer Center Hospital.
Gan To Kagaku Ryoho. 1988 Apr;15(4 Pt 2-2):1256-61.
Type IV of Borrmann's classification is divided into subtypes IVa and IVb on the basis of gross characteristics of the mucosal surface of surgical specimens. Subtype IVa indicates the presence of slight elevation or depression; subtype IVb includes the rest of type IV. The five-year survival rate for patients who had undergone curative gastrectomy was 36.4% for subtype IVa and 15.0% for subtype IVb. The difference in these rates was statistically significant. No significant differences between subtypes IVa and IVb were found, however, with respect to serosal invasion, lymph node metastasis, tumor size, or age or sex distribution. Other clinical and biological factors must therefore be considered to explain these differences in survival rate. The five-year survival rate was 14.3% in patients with scirrhous carcinoma of subtype IVb, and 84.8% in those with scirrhous carcinoma simulating early carcinoma.
Borrmann分类法的IV型根据手术标本黏膜表面的大体特征分为IVa和IVb亚型。IVa亚型表明存在轻微隆起或凹陷；IVb亚型包括IV型的其他情况。接受根治性胃切除术患者的五年生存率，IVa亚型为36.4%，IVb亚型为15.0%。这些比率的差异具有统计学意义。然而，在浆膜侵犯、淋巴结转移、肿瘤大小或年龄及性别分布方面，IVa和IVb亚型之间未发现显著差异。因此，必须考虑其他临床和生物学因素来解释这些生存率的差异。IVb亚型的硬癌患者五年生存率为14.3%，而类似早期癌的硬癌患者五年生存率为84.8%。
