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[胃癌硬癌的治疗方法——特别提及全胃切除术及术后早期化疗]

[Treatment methods for scirrhous carcinoma of the stomach--with special reference to total gastrectomy and chemotherapy in early postoperative period].

作者信息

Nyumura T, Nabeya K, Hamakubo S, Higashino K

机构信息

Second Dept. of Surgery, Kyorin University School of Medicine.

出版信息

Gan To Kagaku Ryoho. 1988 Apr;15(4 Pt 2-2):1262-8.

PMID:2837986
Abstract

The problems existing in surgical treatment methods for scirrhous carcinoma of the stomach include the following: (1) highly advanced cases are frequent, (2) remnants of carcinoma in the proximal line of resection is frequent, and (3) peritoneal dissemination is frequent. Investigations were made on 76 cases of scirrhous carcinoma of the stomach in the care of our department, and the treatment methods in these cases were as follows: 1) Lymph node dissection: Lymphadenectomy of over R2 is performed. 2) Operative methods: When the cancer lesion is in A, AM, M, or MA, and when the proximal line of resection can be made in the excess of 5 cm from the tumor margin, than a sub-total gastrectomy is performed. For cancer lesions in areas other than the above, and for cancer lesions in the above but when the OW cannot be made to measure over 5 cm, a total gastrectomy is performed. In cases in which the cancer invasion extends beyond EGJ and when non-curative resection factors are absent, then an abdomino-thoracic approach is adopted. 3) Chemotherapy: There was some efficacy among the curative resected cases. Since most of the cases result in peritoneal dissemination, chemotherapy is applied during operation and during the early postoperative period.

摘要

胃癌硬癌手术治疗方法中存在的问题如下

(1)进展期病例常见,(2)切除近端癌残留常见,(3)腹膜播散常见。对我科收治的76例胃癌硬癌病例进行了调查,这些病例的治疗方法如下:1)淋巴结清扫:行超过R2的淋巴结切除术。2)手术方法:当癌灶位于A、AM、M或MA区,且切除近端距肿瘤边缘超过5cm时,行胃次全切除术。对于上述区域以外的癌灶,以及上述区域但切除线距肿瘤边缘不足5cm的癌灶,行全胃切除术。当癌浸润超出食管胃交界部且无非根治性切除因素时,采用胸腹联合入路。3)化疗:根治性切除病例中有一定疗效。由于大多数病例会发生腹膜播散,因此在手术期间及术后早期应用化疗。

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